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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 13-112570253-A-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=13&pos=112570253&ref=A&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "13",
"pos": 112570253,
"ref": "A",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_006322.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "NM_006322.6",
"protein_id": "NP_006313.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 907,
"cds_start": null,
"cds_end": null,
"cds_length": 2724,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000261965.8",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_006322.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000261965.8",
"protein_id": "ENSP00000261965.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 907,
"cds_start": null,
"cds_end": null,
"cds_length": 2724,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_006322.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000261965.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000375669.7",
"protein_id": "ENSP00000364821.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 824,
"cds_start": null,
"cds_end": null,
"cds_length": 2475,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000375669.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000464139.5",
"protein_id": "ENSP00000478276.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 439,
"cds_start": null,
"cds_end": null,
"cds_length": 1320,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000464139.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947427.1",
"protein_id": "ENSP00000617486.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 936,
"cds_start": null,
"cds_end": null,
"cds_length": 2811,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947427.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000931607.1",
"protein_id": "ENSP00000601666.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 935,
"cds_start": null,
"cds_end": null,
"cds_length": 2808,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000931607.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865803.1",
"protein_id": "ENSP00000535862.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 906,
"cds_start": null,
"cds_end": null,
"cds_length": 2721,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000865803.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947426.1",
"protein_id": "ENSP00000617485.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 905,
"cds_start": null,
"cds_end": null,
"cds_length": 2718,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947426.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947429.1",
"protein_id": "ENSP00000617488.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 904,
"cds_start": null,
"cds_end": null,
"cds_length": 2715,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947429.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947431.1",
"protein_id": "ENSP00000617490.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 903,
"cds_start": null,
"cds_end": null,
"cds_length": 2712,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947431.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "NM_001286277.2",
"protein_id": "NP_001273206.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 897,
"cds_start": null,
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"cds_length": 2694,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001286277.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
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"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865805.1",
"protein_id": "ENSP00000535864.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 884,
"cds_start": null,
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"cds_length": 2655,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000865805.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865807.1",
"protein_id": "ENSP00000535866.1",
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"aa_start": null,
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"aa_length": 877,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000865807.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
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"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-5075T>G",
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"transcript": "ENST00000931606.1",
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000931606.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947430.1",
"protein_id": "ENSP00000617489.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000947430.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
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"gene_symbol": "TUBGCP3",
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"hgvs_c": "c.77-994T>G",
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"transcript": "ENST00000865801.1",
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"mane_select": null,
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"feature": "ENST00000865801.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
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"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865806.1",
"protein_id": "ENSP00000535865.1",
"transcript_support_level": null,
"aa_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000865806.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865804.1",
"protein_id": "ENSP00000535863.1",
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"aa_start": null,
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"feature": "ENST00000865804.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 1,
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"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "NM_001286278.2",
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"biotype": "protein_coding",
"feature": "NM_001286278.2"
},
{
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"strand": false,
"consequences": [
"intron_variant"
],
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"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
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"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865800.1",
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"feature": "ENST00000865800.1"
},
{
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"strand": false,
"consequences": [
"intron_variant"
],
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"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000947428.1",
"protein_id": "ENSP00000617487.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 784,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947428.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TUBGCP3",
"gene_hgnc_id": 18598,
"hgvs_c": "c.77-994T>G",
"hgvs_p": null,
"transcript": "ENST00000865802.1",
"protein_id": "ENSP00000535861.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000865802.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
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}