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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 13-113004794-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=13&pos=113004794&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "13",
"pos": 113004794,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_001438390.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "NM_001112732.3",
"protein_id": "NP_001106203.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1125,
"cds_start": null,
"cds_end": null,
"cds_length": 3378,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000535094.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001112732.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000535094.7",
"protein_id": "ENSP00000440374.2",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 1125,
"cds_start": null,
"cds_end": null,
"cds_length": 3378,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001112732.3",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000535094.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.92-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000421756.5",
"protein_id": "ENSP00000397285.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1067,
"cds_start": null,
"cds_end": null,
"cds_length": 3204,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000421756.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.73+2811G>C",
"hgvs_p": null,
"transcript": "ENST00000375597.8",
"protein_id": "ENSP00000364747.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 984,
"cds_start": null,
"cds_end": null,
"cds_length": 2955,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000375597.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.179-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438390.1",
"protein_id": "NP_001425319.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1214,
"cds_start": null,
"cds_end": null,
"cds_length": 3645,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001438390.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.170-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438391.1",
"protein_id": "NP_001425320.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1211,
"cds_start": null,
"cds_end": null,
"cds_length": 3636,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001438391.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000884942.1",
"protein_id": "ENSP00000555001.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1203,
"cds_start": null,
"cds_end": null,
"cds_length": 3612,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884942.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000884941.1",
"protein_id": "ENSP00000555000.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1197,
"cds_start": null,
"cds_end": null,
"cds_length": 3594,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884941.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000884943.1",
"protein_id": "ENSP00000555002.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1195,
"cds_start": null,
"cds_end": null,
"cds_length": 3588,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884943.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.179-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438759.1",
"protein_id": "NP_001425688.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1183,
"cds_start": null,
"cds_end": null,
"cds_length": 3552,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001438759.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "NM_001437889.1",
"protein_id": "NP_001424818.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1181,
"cds_start": null,
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"cds_length": 3546,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001437889.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 32,
"intron_rank": 1,
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"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000453297.6",
"protein_id": "ENSP00000392953.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1181,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000453297.6"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.170-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438392.1",
"protein_id": "NP_001425321.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1180,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001438392.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
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],
"exon_rank": null,
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"exon_count": 32,
"intron_rank": 1,
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"gene_symbol": "MCF2L",
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"hgvs_c": "c.73+2811G>C",
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"transcript": "NM_001438760.1",
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"biotype": "protein_coding",
"feature": "NM_001438760.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.26-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438761.1",
"protein_id": "NP_001425690.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001438761.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 30,
"intron_rank": 1,
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"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.179-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438762.1",
"protein_id": "NP_001425691.1",
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"biotype": "protein_coding",
"feature": "NM_001438762.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.170-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438393.1",
"protein_id": "NP_001425322.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001438393.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "NM_001438763.1",
"protein_id": "NP_001425692.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1150,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001438763.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.73+2811G>C",
"hgvs_p": null,
"transcript": "NM_001320815.2",
"protein_id": "NP_001307744.1",
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"biotype": "protein_coding",
"feature": "NM_001320815.2"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 31,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.53-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000420013.6",
"protein_id": "ENSP00000404422.2",
"transcript_support_level": 4,
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},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.80-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000920919.1",
"protein_id": "ENSP00000590978.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000920919.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "MCF2L",
"gene_hgnc_id": 14576,
"hgvs_c": "c.170-9969G>C",
"hgvs_p": null,
"transcript": "ENST00000375608.7",
"protein_id": "ENSP00000364758.3",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1137,
"cds_start": null,
"cds_end": null,
"cds_length": 3414,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000375608.7"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
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