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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 14-95087805-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=14&pos=95087805&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "14",
"pos": 95087805,
"ref": "T",
"alt": "C",
"effect": "3_prime_UTR_variant",
"transcript": "ENST00000343455.8",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 27,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_177438.3",
"protein_id": "NP_803187.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1922,
"cds_start": -4,
"cds_end": null,
"cds_length": 5769,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10384,
"mane_select": "ENST00000343455.8",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 27,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "ENST00000343455.8",
"protein_id": "ENSP00000343745.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1922,
"cds_start": -4,
"cds_end": null,
"cds_length": 5769,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10384,
"mane_select": "NM_177438.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "ENST00000529720.2",
"protein_id": "ENSP00000433926.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1922,
"cds_start": -4,
"cds_end": null,
"cds_length": 5769,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10374,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "ENST00000531162.7",
"protein_id": "ENSP00000433060.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1922,
"cds_start": -4,
"cds_end": null,
"cds_length": 5769,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10453,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.*5112A>G",
"hgvs_p": null,
"transcript": "ENST00000675540.2",
"protein_id": "ENSP00000501988.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10356,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 27,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.*3084A>G",
"hgvs_p": null,
"transcript": "ENST00000696733.1",
"protein_id": "ENSP00000512838.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10006,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 28,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.*3117A>G",
"hgvs_p": null,
"transcript": "ENST00000696734.1",
"protein_id": "ENSP00000512839.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10081,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 19,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.8725A>G",
"hgvs_p": null,
"transcript": "ENST00000696920.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10287,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 26,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.9568A>G",
"hgvs_p": null,
"transcript": "ENST00000696921.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 11130,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 28,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.11393A>G",
"hgvs_p": null,
"transcript": "ENST00000696922.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 12694,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.*3117A>G",
"hgvs_p": null,
"transcript": "ENST00000696923.1",
"protein_id": "ENSP00000512976.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 10197,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.*3084A>G",
"hgvs_p": null,
"transcript": "ENST00000696924.1",
"protein_id": "ENSP00000512977.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 10167,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 26,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.9064A>G",
"hgvs_p": null,
"transcript": "NR_172716.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
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"aa_length": null,
"cds_start": -4,
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"mane_select": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
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],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
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"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.8897A>G",
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"transcript": "NR_172718.1",
"protein_id": null,
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},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 27,
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"exon_count": 27,
"intron_rank": null,
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"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.8730A>G",
"hgvs_p": null,
"transcript": "NR_172719.1",
"protein_id": null,
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"aa_start": null,
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"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 28,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": null,
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"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "n.8933A>G",
"hgvs_p": null,
"transcript": "NR_172720.1",
"protein_id": null,
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 27,
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"exon_count": 27,
"intron_rank": null,
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"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001271282.3",
"protein_id": "NP_001258211.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1922,
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"cdna_start": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 27,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001291628.2",
"protein_id": "NP_001278557.1",
"transcript_support_level": null,
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"aa_length": 1922,
"cds_start": -4,
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"cdna_start": null,
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},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001395677.1",
"protein_id": "NP_001382606.1",
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},
{
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],
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"exon_count": 27,
"intron_rank": null,
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"gene_symbol": "DICER1",
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"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001395678.1",
"protein_id": "NP_001382607.1",
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"feature": null
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 29,
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"exon_count": 29,
"intron_rank": null,
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"gene_symbol": "DICER1",
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"hgvs_c": "c.*2693A>G",
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"transcript": "NM_001395679.1",
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001395680.1",
"protein_id": "NP_001382609.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1922,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 10390,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "DICER1",
"gene_hgnc_id": 17098,
"hgvs_c": "c.*2693A>G",
"hgvs_p": null,
"transcript": "NM_001395682.1",
"protein_id": "NP_001382611.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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