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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 15-68793418-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=15&pos=68793418&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "15",
"pos": 68793418,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_006305.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "NM_006305.4",
"protein_id": "NP_006296.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 249,
"cds_start": null,
"cds_end": null,
"cds_length": 750,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000465139.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_006305.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000465139.6",
"protein_id": "ENSP00000417864.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 249,
"cds_start": null,
"cds_end": null,
"cds_length": 750,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_006305.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000465139.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5226A>G",
"hgvs_p": null,
"transcript": "ENST00000882112.1",
"protein_id": "ENSP00000552171.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 340,
"cds_start": null,
"cds_end": null,
"cds_length": 1023,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000882112.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5226A>G",
"hgvs_p": null,
"transcript": "ENST00000923067.1",
"protein_id": "ENSP00000593126.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 339,
"cds_start": null,
"cds_end": null,
"cds_length": 1020,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000923067.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000882110.1",
"protein_id": "ENSP00000552169.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 258,
"cds_start": null,
"cds_end": null,
"cds_length": 777,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000882110.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000882106.1",
"protein_id": "ENSP00000552165.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000882106.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000882107.1",
"protein_id": "ENSP00000552166.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000882107.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000882108.1",
"protein_id": "ENSP00000552167.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000882108.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000923059.1",
"protein_id": "ENSP00000593118.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 247,
"cds_start": null,
"cds_end": null,
"cds_length": 744,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000923059.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000923061.1",
"protein_id": "ENSP00000593120.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000923061.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000923062.1",
"protein_id": "ENSP00000593121.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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"transcript": "ENST00000923068.1",
"protein_id": "ENSP00000593127.1",
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"aa_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000923068.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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"transcript": "ENST00000882113.1",
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},
{
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],
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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},
{
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"strand": false,
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],
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"intron_rank": 1,
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"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000923073.1",
"protein_id": "ENSP00000593132.1",
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},
{
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],
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"gene_symbol": "ANP32A",
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"transcript": "ENST00000923077.1",
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},
{
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"strand": false,
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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"transcript": "ENST00000923070.1",
"protein_id": "ENSP00000593129.1",
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},
{
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],
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"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000967540.1",
"protein_id": "ENSP00000637599.1",
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},
{
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],
"exon_rank": null,
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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},
{
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],
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},
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],
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"gene_symbol": "ANP32A",
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"hgvs_c": "c.55-5499A>G",
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"transcript": "ENST00000923069.1",
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"biotype": "protein_coding",
"feature": "ENST00000923069.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANP32A",
"gene_hgnc_id": 13233,
"hgvs_c": "c.55-5499A>G",
"hgvs_p": null,
"transcript": "ENST00000560303.1",
"protein_id": "ENSP00000453838.1",
"transcript_support_level": 5,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
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"feature": "ENST00000560303.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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}