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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 15-80100347-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=15&pos=80100347&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "15",
"pos": 80100347,
"ref": "A",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000261749.11",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "NM_019006.4",
"protein_id": "NP_061879.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1706,
"mane_select": "ENST00000261749.11",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "ENST00000261749.11",
"protein_id": "ENSP00000261749.6",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1706,
"mane_select": "NM_019006.4",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "ENST00000558494.5",
"protein_id": "ENSP00000454137.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1472,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "ENST00000559835.5",
"protein_id": "ENSP00000453291.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1446,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "ENST00000561060.5",
"protein_id": "ENSP00000452735.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 891,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "NM_001242911.2",
"protein_id": "NP_001229840.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1543,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "NM_001242912.2",
"protein_id": "NP_001229841.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1622,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "NM_001242913.2",
"protein_id": "NP_001229842.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1693,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "NM_001242914.2",
"protein_id": "NP_001229843.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1701,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "NM_001242915.2",
"protein_id": "NP_001229844.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
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"cds_length": 627,
"cdna_start": null,
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"cdna_length": 1495,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "NM_001242916.2",
"protein_id": "NP_001229845.1",
"transcript_support_level": null,
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"cds_start": -4,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "ZFAND6",
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"hgvs_c": "c.-17-19981A>G",
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"transcript": "ENST00000558087.5",
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},
{
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],
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"gene_symbol": "ZFAND6",
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"hgvs_c": "c.-18+1769A>G",
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"protein_id": "ENSP00000453709.1",
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},
{
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],
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"gene_symbol": "ZFAND6",
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"hgvs_c": "c.-17-19981A>G",
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"transcript": "ENST00000613266.4",
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},
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],
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"hgvs_c": "c.-18+1769A>G",
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},
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],
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"gene_symbol": "ZFAND6",
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},
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],
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"gene_symbol": "ZFAND6",
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"transcript": "NM_001242917.2",
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},
{
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],
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"gene_symbol": "ZFAND6",
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"hgvs_c": "c.-61-14680A>G",
"hgvs_p": null,
"transcript": "ENST00000559157.6",
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},
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],
"exon_rank": null,
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"gene_symbol": "ZFAND6",
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],
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},
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],
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},
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"consequences": [
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],
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"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-17-19981A>G",
"hgvs_p": null,
"transcript": "NM_001242918.2",
"protein_id": "NP_001229847.1",
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},
{
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 6,
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"intron_rank_end": null,
"gene_symbol": "ZFAND6",
"gene_hgnc_id": 30164,
"hgvs_c": "c.-18+1769A>G",
"hgvs_p": null,
"transcript": "ENST00000558997.5",
"protein_id": "ENSP00000453571.1",
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