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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 16-14185624-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=16&pos=14185624&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "16",
"pos": 14185624,
"ref": "G",
"alt": "A",
"effect": "intron_variant",
"transcript": "ENST00000571589.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "NM_001308142.2",
"protein_id": "NP_001295071.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1099,
"cds_start": -4,
"cds_end": null,
"cds_length": 3300,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8804,
"mane_select": "ENST00000571589.6",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "ENST00000571589.6",
"protein_id": "ENSP00000459626.2",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 1099,
"cds_start": -4,
"cds_end": null,
"cds_length": 3300,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8804,
"mane_select": "NM_001308142.2",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "ENST00000574045.5",
"protein_id": "ENSP00000459205.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1049,
"cds_start": -4,
"cds_end": null,
"cds_length": 3150,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3309,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "NM_001365412.2",
"protein_id": "NP_001352341.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1053,
"cds_start": -4,
"cds_end": null,
"cds_length": 3162,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8828,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "NM_014048.4",
"protein_id": "NP_054767.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1049,
"cds_start": -4,
"cds_end": null,
"cds_length": 3150,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8666,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "ENST00000318282.9",
"protein_id": "ENSP00000339086.4",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1049,
"cds_start": -4,
"cds_end": null,
"cds_length": 3150,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8608,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "ENST00000574998.5",
"protein_id": "ENSP00000458340.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 69,
"cds_start": -4,
"cds_end": null,
"cds_length": 210,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 545,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "n.129-24619G>A",
"hgvs_p": null,
"transcript": "ENST00000575768.1",
"protein_id": null,
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 389,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "XM_005255452.4",
"protein_id": "XP_005255509.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1099,
"cds_start": -4,
"cds_end": null,
"cds_length": 3300,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8978,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "XM_006720909.5",
"protein_id": "XP_006720972.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1099,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "XM_011522568.3",
"protein_id": "XP_011520870.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 3,
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"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_017023501.3",
"protein_id": "XP_016878990.1",
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},
{
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 3,
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"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_017023502.1",
"protein_id": "XP_016878991.1",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 18,
"intron_rank": 4,
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"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_047434390.1",
"protein_id": "XP_047290346.1",
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},
{
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],
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"gene_symbol": "MRTFB",
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"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_047434391.1",
"protein_id": "XP_047290347.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 18,
"intron_rank": 4,
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"gene_symbol": "MRTFB",
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"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_047434392.1",
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},
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],
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"gene_symbol": "MRTFB",
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"hgvs_c": "c.155-24619G>A",
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"transcript": "XM_047434393.1",
"protein_id": "XP_047290349.1",
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},
{
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"strand": true,
"consequences": [
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],
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"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "XM_047434394.1",
"protein_id": "XP_047290350.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 4,
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"gene_symbol": "MRTFB",
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"hgvs_c": "c.155-24619G>A",
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],
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"gene_symbol": "MRTFB",
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"hgvs_c": "c.155-24619G>A",
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},
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"strand": true,
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],
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"intron_rank": 5,
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"gene_symbol": "MRTFB",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 15,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.44-24619G>A",
"hgvs_p": null,
"transcript": "XM_017023503.3",
"protein_id": "XP_016878992.1",
"transcript_support_level": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MRTFB",
"gene_hgnc_id": 29819,
"hgvs_c": "c.155-24619G>A",
"hgvs_p": null,
"transcript": "XM_047434398.1",
"protein_id": "XP_047290354.1",
"transcript_support_level": null,
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}