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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 16-15603938-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=16&pos=15603938&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "16",
"pos": 15603938,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_014647.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4413+230G>A",
"hgvs_p": null,
"transcript": "NM_014647.4",
"protein_id": "NP_055462.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1742,
"cds_start": null,
"cds_end": null,
"cds_length": 5229,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000396368.8",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_014647.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4413+230G>A",
"hgvs_p": null,
"transcript": "ENST00000396368.8",
"protein_id": "ENSP00000379654.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1742,
"cds_start": null,
"cds_end": null,
"cds_length": 5229,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_014647.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000396368.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4413+230G>A",
"hgvs_p": null,
"transcript": "ENST00000551742.5",
"protein_id": "ENSP00000450309.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1742,
"cds_start": null,
"cds_end": null,
"cds_length": 5229,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000551742.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4404+230G>A",
"hgvs_p": null,
"transcript": "ENST00000548025.5",
"protein_id": "ENSP00000449376.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1739,
"cds_start": null,
"cds_end": null,
"cds_length": 5220,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000548025.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4416+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892734.1",
"protein_id": "ENSP00000562793.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1743,
"cds_start": null,
"cds_end": null,
"cds_length": 5232,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892734.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4413+230G>A",
"hgvs_p": null,
"transcript": "NM_001184998.2",
"protein_id": "NP_001171927.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1742,
"cds_start": null,
"cds_end": null,
"cds_length": 5229,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001184998.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4410+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892732.1",
"protein_id": "ENSP00000562791.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1741,
"cds_start": null,
"cds_end": null,
"cds_length": 5226,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892732.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 23,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4410+230G>A",
"hgvs_p": null,
"transcript": "ENST00000912644.1",
"protein_id": "ENSP00000582703.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1741,
"cds_start": null,
"cds_end": null,
"cds_length": 5226,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000912644.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4404+230G>A",
"hgvs_p": null,
"transcript": "NM_001184999.2",
"protein_id": "NP_001171928.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1739,
"cds_start": null,
"cds_end": null,
"cds_length": 5220,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001184999.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4386+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892737.1",
"protein_id": "ENSP00000562796.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1733,
"cds_start": null,
"cds_end": null,
"cds_length": 5202,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892737.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.4383+230G>A",
"hgvs_p": null,
"transcript": "ENST00000912645.1",
"protein_id": "ENSP00000582704.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1732,
"cds_start": null,
"cds_end": null,
"cds_length": 5199,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000912645.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3993+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892740.1",
"protein_id": "ENSP00000562799.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1602,
"cds_start": null,
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"cds_length": 4809,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892740.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3984+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892736.1",
"protein_id": "ENSP00000562795.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1599,
"cds_start": null,
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"cds_length": 4800,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892736.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3957+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892738.1",
"protein_id": "ENSP00000562797.1",
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"biotype": "protein_coding",
"feature": "ENST00000892738.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3918+230G>A",
"hgvs_p": null,
"transcript": "ENST00000540441.6",
"protein_id": "ENSP00000439819.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1577,
"cds_start": null,
"cds_end": null,
"cds_length": 4734,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000540441.6"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3879+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892739.1",
"protein_id": "ENSP00000562798.1",
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000892739.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3876+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892733.1",
"protein_id": "ENSP00000562792.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1563,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892733.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3873+230G>A",
"hgvs_p": null,
"transcript": "ENST00000912641.1",
"protein_id": "ENSP00000582700.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1562,
"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000912641.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 27,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3849+230G>A",
"hgvs_p": null,
"transcript": "ENST00000912642.1",
"protein_id": "ENSP00000582701.1",
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"feature": "ENST00000912642.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
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"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3846+230G>A",
"hgvs_p": null,
"transcript": "ENST00000912643.1",
"protein_id": "ENSP00000582702.1",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "MARF1",
"gene_hgnc_id": 29562,
"hgvs_c": "c.3420+230G>A",
"hgvs_p": null,
"transcript": "ENST00000892735.1",
"protein_id": "ENSP00000562794.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1411,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892735.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "BMERB1",
"gene_hgnc_id": 19213,
"hgvs_c": "c.*12+12823C>T",
"hgvs_p": null,
"transcript": "ENST00000565857.1",
"protein_id": "ENSP00000456084.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 114,
"cds_start": null,
"cds_end": null,
"cds_length": 345,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000565857.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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],
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}