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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-78798899-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=78798899&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 78798899,
"ref": "A",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000449938.7",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385174.1",
"protein_id": "NP_001372103.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5872,
"mane_select": "ENST00000449938.7",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "ENST00000449938.7",
"protein_id": "ENSP00000401119.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5872,
"mane_select": "NM_001385174.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "ENST00000542802.7",
"protein_id": "ENSP00000441214.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6063,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "n.3240+9T>C",
"hgvs_p": null,
"transcript": "ENST00000589225.5",
"protein_id": "ENSP00000467280.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5885,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3243+9T>C",
"hgvs_p": null,
"transcript": "NM_001385169.1",
"protein_id": "NP_001372098.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1124,
"cds_start": -4,
"cds_end": null,
"cds_length": 3375,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3925,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001321291.2",
"protein_id": "NP_001308220.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6208,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385170.1",
"protein_id": "NP_001372099.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6216,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385171.1",
"protein_id": "NP_001372100.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6329,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385172.1",
"protein_id": "NP_001372101.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6047,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385173.1",
"protein_id": "NP_001372102.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
"cds_end": null,
"cds_length": 3372,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3922,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385175.1",
"protein_id": "NP_001372104.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 5895,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "NM_001385176.1",
"protein_id": "NP_001372105.1",
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"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "ENST00000312010.10",
"protein_id": "ENSP00000310590.6",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1123,
"cds_start": -4,
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"cdna_start": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.3240+9T>C",
"hgvs_p": null,
"transcript": "ENST00000592231.6",
"protein_id": "ENSP00000465698.2",
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"aa_start": null,
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"cds_start": -4,
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 18,
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"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.2745+9T>C",
"hgvs_p": null,
"transcript": "NM_001385177.1",
"protein_id": "NP_001372106.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 18,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.2745+9T>C",
"hgvs_p": null,
"transcript": "NM_001385178.1",
"protein_id": "NP_001372107.1",
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},
{
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 19,
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"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.2610+9T>C",
"hgvs_p": null,
"transcript": "NM_001385179.1",
"protein_id": "NP_001372108.1",
"transcript_support_level": null,
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"cds_start": -4,
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"feature": null
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 18,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.2583+9T>C",
"hgvs_p": null,
"transcript": "NM_001385180.1",
"protein_id": "NP_001372109.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 904,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "c.171+9T>C",
"hgvs_p": null,
"transcript": "ENST00000588130.5",
"protein_id": "ENSP00000464746.1",
"transcript_support_level": 2,
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "USP36",
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"hgvs_c": "n.81+9T>C",
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"transcript": "ENST00000587010.5",
"protein_id": "ENSP00000465679.1",
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},
{
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"strand": false,
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],
"exon_rank": null,
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"intron_rank": 18,
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"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "n.*2652+9T>C",
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"transcript": "ENST00000693020.1",
"protein_id": "ENSP00000510682.1",
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},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "n.3492+9T>C",
"hgvs_p": null,
"transcript": "NR_169581.1",
"protein_id": null,
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"aa_start": null,
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"cds_start": -4,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "USP36",
"gene_hgnc_id": 20062,
"hgvs_c": "n.3492+9T>C",
"hgvs_p": null,
"transcript": "NR_169582.1",
"protein_id": null,
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"aa_start": null,
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"aa_length": null,
"cds_start": -4,
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"mane_select": null,
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"feature": null
},
{
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