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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 18-36672786-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=18&pos=36672786&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "18",
"pos": 36672786,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_001281740.3",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1836-8650C>T",
"hgvs_p": null,
"transcript": "NM_001281740.3",
"protein_id": "NP_001268669.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1622,
"cds_start": -4,
"cds_end": null,
"cds_length": 4869,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5682,
"mane_select": "ENST00000590592.6",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1836-8650C>T",
"hgvs_p": null,
"transcript": "ENST00000590592.6",
"protein_id": "ENSP00000466937.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1622,
"cds_start": -4,
"cds_end": null,
"cds_length": 4869,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5682,
"mane_select": "NM_001281740.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1311-8650C>T",
"hgvs_p": null,
"transcript": "ENST00000257209.8",
"protein_id": "ENSP00000257209.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1439,
"cds_start": -4,
"cds_end": null,
"cds_length": 4320,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4967,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1311-8650C>T",
"hgvs_p": null,
"transcript": "ENST00000359247.8",
"protein_id": "ENSP00000352186.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1422,
"cds_start": -4,
"cds_end": null,
"cds_length": 4269,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4518,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.591-8650C>T",
"hgvs_p": null,
"transcript": "ENST00000592930.5",
"protein_id": "ENSP00000468163.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1199,
"cds_start": -4,
"cds_end": null,
"cds_length": 3600,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4126,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1311-8650C>T",
"hgvs_p": null,
"transcript": "NM_025135.5",
"protein_id": "NP_079411.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1439,
"cds_start": -4,
"cds_end": null,
"cds_length": 4320,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5133,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.1311-8650C>T",
"hgvs_p": null,
"transcript": "NM_001281739.3",
"protein_id": "NP_001268668.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1422,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "c.276+14656C>T",
"hgvs_p": null,
"transcript": "ENST00000591635.5",
"protein_id": "ENSP00000467195.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 635,
"cds_start": -4,
"cds_end": null,
"cds_length": 1908,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3035,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "FHOD3",
"gene_hgnc_id": 26178,
"hgvs_c": "n.1430-8650C>T",
"hgvs_p": null,
"transcript": "ENST00000589114.5",
"protein_id": null,
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 4154,
"mane_select": null,
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"feature": null
},
{
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"protein_coding": true,
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"consequences": [
"intron_variant"
],
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"gene_symbol": "FHOD3",
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"hgvs_c": "c.1836-8487C>T",
"hgvs_p": null,
"transcript": "XM_011526189.2",
"protein_id": "XP_011524491.1",
"transcript_support_level": null,
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},
{
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"gene_symbol": "FHOD3",
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"hgvs_c": "c.1836-8487C>T",
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"transcript": "XM_011526190.3",
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},
{
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],
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],
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],
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"gene_symbol": "FHOD3",
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"hgvs_c": "c.1761-8650C>T",
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],
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"gene_symbol": "FHOD3",
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}
],
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}