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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 2-152721872-C-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=152721872&ref=C&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "2",
"pos": 152721872,
"ref": "C",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000326446.10",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.454+1286C>G",
"hgvs_p": null,
"transcript": "NM_152522.7",
"protein_id": "NP_689735.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 226,
"cds_start": -4,
"cds_end": null,
"cds_length": 681,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3242,
"mane_select": "ENST00000326446.10",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.454+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000326446.10",
"protein_id": "ENSP00000315357.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 226,
"cds_start": -4,
"cds_end": null,
"cds_length": 681,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3242,
"mane_select": "NM_152522.7",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.1904C>G",
"hgvs_p": null,
"transcript": "ENST00000686951.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4130,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.1879C>G",
"hgvs_p": null,
"transcript": "ENST00000688171.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4049,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.1391C>G",
"hgvs_p": null,
"transcript": "ENST00000690703.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3618,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.400+2848C>G",
"hgvs_p": null,
"transcript": "ENST00000692399.1",
"protein_id": "ENSP00000510087.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 208,
"cds_start": -4,
"cds_end": null,
"cds_length": 627,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1564,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.454+1286C>G",
"hgvs_p": null,
"transcript": "NM_001371972.1",
"protein_id": "NP_001358901.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 195,
"cds_start": -4,
"cds_end": null,
"cds_length": 588,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3138,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.454+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000686080.1",
"protein_id": "ENSP00000509648.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 195,
"cds_start": -4,
"cds_end": null,
"cds_length": 588,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1927,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.454+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000687504.1",
"protein_id": "ENSP00000508902.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 153,
"cds_start": -4,
"cds_end": null,
"cds_length": 462,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1088,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.166+1286C>G",
"hgvs_p": null,
"transcript": "NM_001350068.2",
"protein_id": "NP_001336997.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 130,
"cds_start": -4,
"cds_end": null,
"cds_length": 393,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3374,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.-96+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000463690.2",
"protein_id": "ENSP00000508954.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 43,
"cds_start": -4,
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"cds_length": 132,
"cdna_start": null,
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"cdna_length": 2170,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
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"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.-96+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000686839.1",
"protein_id": "ENSP00000508917.1",
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"aa_start": null,
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"cds_start": -4,
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.-146+1286C>G",
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"transcript": "ENST00000688012.1",
"protein_id": "ENSP00000508539.1",
"transcript_support_level": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 2,
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "c.-96+1286C>G",
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"transcript": "ENST00000688293.1",
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},
{
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"strand": true,
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"intron_variant"
],
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "c.-96+3877C>G",
"hgvs_p": null,
"transcript": "ENST00000689155.1",
"protein_id": "ENSP00000508418.1",
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 2,
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"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "c.-44+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000690727.1",
"protein_id": "ENSP00000510402.1",
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},
{
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],
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "c.-96+1286C>G",
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"transcript": "ENST00000691523.1",
"protein_id": "ENSP00000508751.1",
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},
{
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"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
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"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.*111+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000425034.6",
"protein_id": "ENSP00000395052.2",
"transcript_support_level": 2,
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},
{
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"protein_coding": false,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 2,
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "n.454+1286C>G",
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"transcript": "ENST00000455875.6",
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},
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],
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "n.454+1286C>G",
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},
{
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"strand": true,
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],
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"intron_rank": 2,
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"gene_symbol": "ARL6IP6",
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"hgvs_c": "n.454+1286C>G",
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"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.618+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000692124.1",
"protein_id": null,
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"mane_select": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ARL6IP6",
"gene_hgnc_id": 24048,
"hgvs_c": "n.618+1286C>G",
"hgvs_p": null,
"transcript": "ENST00000693573.1",
"protein_id": null,
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}