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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 2-182928655-T-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=182928655&ref=T&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "2",
"pos": 182928655,
"ref": "T",
"alt": "A",
"effect": "intron_variant",
"transcript": "NM_205842.3",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3070+128A>T",
"hgvs_p": null,
"transcript": "NM_013436.5",
"protein_id": "NP_038464.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1128,
"cds_start": null,
"cds_end": null,
"cds_length": 3387,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000361354.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_013436.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3070+128A>T",
"hgvs_p": null,
"transcript": "ENST00000361354.9",
"protein_id": "ENSP00000355348.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1128,
"cds_start": null,
"cds_end": null,
"cds_length": 3387,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_013436.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000361354.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 29,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3088+128A>T",
"hgvs_p": null,
"transcript": "ENST00000360982.2",
"protein_id": "ENSP00000354251.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1134,
"cds_start": null,
"cds_end": null,
"cds_length": 3405,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000360982.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 29,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3088+128A>T",
"hgvs_p": null,
"transcript": "NM_205842.3",
"protein_id": "NP_995314.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1134,
"cds_start": null,
"cds_end": null,
"cds_length": 3405,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_205842.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3085+128A>T",
"hgvs_p": null,
"transcript": "ENST00000888539.1",
"protein_id": "ENSP00000558598.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1133,
"cds_start": null,
"cds_end": null,
"cds_length": 3402,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000888539.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 29,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3082+128A>T",
"hgvs_p": null,
"transcript": "NM_001437267.1",
"protein_id": "NP_001424196.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1132,
"cds_start": null,
"cds_end": null,
"cds_length": 3399,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001437267.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 29,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3082+128A>T",
"hgvs_p": null,
"transcript": "ENST00000703824.1",
"protein_id": "ENSP00000515489.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1132,
"cds_start": null,
"cds_end": null,
"cds_length": 3399,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000703824.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3064+128A>T",
"hgvs_p": null,
"transcript": "NM_001437266.1",
"protein_id": "NP_001424195.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1126,
"cds_start": null,
"cds_end": null,
"cds_length": 3381,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001437266.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3064+128A>T",
"hgvs_p": null,
"transcript": "ENST00000703825.1",
"protein_id": "ENSP00000515490.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1126,
"cds_start": null,
"cds_end": null,
"cds_length": 3381,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000703825.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3064+128A>T",
"hgvs_p": null,
"transcript": "ENST00000939370.1",
"protein_id": "ENSP00000609429.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1126,
"cds_start": null,
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"cds_length": 3381,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000939370.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 28,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3064+128A>T",
"hgvs_p": null,
"transcript": "ENST00000939372.1",
"protein_id": "ENSP00000609431.1",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000939372.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 31,
"intron_rank": 28,
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"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3049+128A>T",
"hgvs_p": null,
"transcript": "ENST00000966159.1",
"protein_id": "ENSP00000636218.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000966159.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 30,
"intron_rank": 27,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.3013+128A>T",
"hgvs_p": null,
"transcript": "ENST00000888538.1",
"protein_id": "ENSP00000558597.1",
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000888538.1"
},
{
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"protein_coding": true,
"strand": false,
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],
"exon_rank": null,
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"gene_symbol": "NCKAP1",
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"transcript": "ENST00000966167.1",
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"biotype": "protein_coding",
"feature": "ENST00000966167.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 30,
"intron_rank": 27,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.2971+128A>T",
"hgvs_p": null,
"transcript": "ENST00000888537.1",
"protein_id": "ENSP00000558596.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000888537.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 30,
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"gene_symbol": "NCKAP1",
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"hgvs_c": "c.2959+128A>T",
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"transcript": "ENST00000888541.1",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 30,
"intron_rank": 27,
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"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.2944+128A>T",
"hgvs_p": null,
"transcript": "ENST00000966160.1",
"protein_id": "ENSP00000636219.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 27,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.2932+128A>T",
"hgvs_p": null,
"transcript": "ENST00000888540.1",
"protein_id": "ENSP00000558599.1",
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},
{
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"strand": false,
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],
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"intron_rank": 27,
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"gene_symbol": "NCKAP1",
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"hgvs_c": "c.2926+128A>T",
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},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 27,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
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"hgvs_c": "c.2851+128A>T",
"hgvs_p": null,
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
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"intron_rank": 26,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.2791+128A>T",
"hgvs_p": null,
"transcript": "ENST00000966166.1",
"protein_id": "ENSP00000636225.1",
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000966166.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 26,
"intron_rank_end": null,
"gene_symbol": "NCKAP1",
"gene_hgnc_id": 7666,
"hgvs_c": "c.2785+128A>T",
"hgvs_p": null,
"transcript": "ENST00000966169.1",
"protein_id": "ENSP00000636228.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000966169.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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}
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}