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GeneBe API Showcase

This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.

API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.

Documentation & Advanced Usage

Complete API documentation:docs.genebe.net/docs/api/overview/

Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/

Python client for pandas:pypi.org/project/genebe/

Java CLI for VCF files:github.com/pstawinski/genebe-cli

All tools documented at:docs.genebe.net

API Request Examples for Variant: 2-27459754-T-C (hg38)

Bash / cURL Example

bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=27459754&ref=T&alt=C&genome=hg38&allGenes=true"

API Response

json
{
  "variants": [
    {
      "chr": "2",
      "pos": 27459754,
      "ref": "T",
      "alt": "C",
      "effect": "missense_variant",
      "transcript": "ENST00000260570.8",
      "consequences": [
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 48,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2597A>G",
          "hgvs_p": "p.Gln866Arg",
          "transcript": "NM_015662.3",
          "protein_id": "NP_056477.1",
          "transcript_support_level": null,
          "aa_start": 866,
          "aa_end": null,
          "aa_length": 1749,
          "cds_start": 2597,
          "cds_end": null,
          "cds_length": 5250,
          "cdna_start": 2687,
          "cdna_end": null,
          "cdna_length": 5395,
          "mane_select": "ENST00000260570.8",
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": true,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 48,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2597A>G",
          "hgvs_p": "p.Gln866Arg",
          "transcript": "ENST00000260570.8",
          "protein_id": "ENSP00000260570.3",
          "transcript_support_level": 1,
          "aa_start": 866,
          "aa_end": null,
          "aa_length": 1749,
          "cds_start": 2597,
          "cds_end": null,
          "cds_length": 5250,
          "cdna_start": 2687,
          "cdna_end": null,
          "cdna_length": 5395,
          "mane_select": "NM_015662.3",
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 48,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2531A>G",
          "hgvs_p": "p.Gln844Arg",
          "transcript": "NM_001410739.1",
          "protein_id": "NP_001397668.1",
          "transcript_support_level": null,
          "aa_start": 844,
          "aa_end": null,
          "aa_length": 1727,
          "cds_start": 2531,
          "cds_end": null,
          "cds_length": 5184,
          "cdna_start": 2621,
          "cdna_end": null,
          "cdna_length": 5329,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 48,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2531A>G",
          "hgvs_p": "p.Gln844Arg",
          "transcript": "ENST00000675690.1",
          "protein_id": "ENSP00000502283.1",
          "transcript_support_level": null,
          "aa_start": 844,
          "aa_end": null,
          "aa_length": 1727,
          "cds_start": 2531,
          "cds_end": null,
          "cds_length": 5184,
          "cdna_start": 2632,
          "cdna_end": null,
          "cdna_length": 5340,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 25,
          "exon_rank_end": null,
          "exon_count": 49,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2534A>G",
          "hgvs_p": "p.Gln845Arg",
          "transcript": "XM_006711986.4",
          "protein_id": "XP_006712049.1",
          "transcript_support_level": null,
          "aa_start": 845,
          "aa_end": null,
          "aa_length": 1728,
          "cds_start": 2534,
          "cds_end": null,
          "cds_length": 5187,
          "cdna_start": 2771,
          "cdna_end": null,
          "cdna_length": 5479,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 47,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2597A>G",
          "hgvs_p": "p.Gln866Arg",
          "transcript": "XM_006711987.2",
          "protein_id": "XP_006712050.1",
          "transcript_support_level": null,
          "aa_start": 866,
          "aa_end": null,
          "aa_length": 1716,
          "cds_start": 2597,
          "cds_end": null,
          "cds_length": 5151,
          "cdna_start": 2687,
          "cdna_end": null,
          "cdna_length": 5296,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 47,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2531A>G",
          "hgvs_p": "p.Gln844Arg",
          "transcript": "XM_047443900.1",
          "protein_id": "XP_047299856.1",
          "transcript_support_level": null,
          "aa_start": 844,
          "aa_end": null,
          "aa_length": 1694,
          "cds_start": 2531,
          "cds_end": null,
          "cds_length": 5085,
          "cdna_start": 2621,
          "cdna_end": null,
          "cdna_length": 5230,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 21,
          "exon_rank_end": null,
          "exon_count": 45,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.1916A>G",
          "hgvs_p": "p.Gln639Arg",
          "transcript": "XM_047443901.1",
          "protein_id": "XP_047299857.1",
          "transcript_support_level": null,
          "aa_start": 639,
          "aa_end": null,
          "aa_length": 1522,
          "cds_start": 1916,
          "cds_end": null,
          "cds_length": 4569,
          "cdna_start": 2400,
          "cdna_end": null,
          "cdna_length": 5108,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 21,
          "exon_rank_end": null,
          "exon_count": 45,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.1916A>G",
          "hgvs_p": "p.Gln639Arg",
          "transcript": "XM_047443902.1",
          "protein_id": "XP_047299858.1",
          "transcript_support_level": null,
          "aa_start": 639,
          "aa_end": null,
          "aa_length": 1522,
          "cds_start": 1916,
          "cds_end": null,
          "cds_length": 4569,
          "cdna_start": 2309,
          "cdna_end": null,
          "cdna_length": 5017,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 36,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2597A>G",
          "hgvs_p": "p.Gln866Arg",
          "transcript": "XM_011532758.2",
          "protein_id": "XP_011531060.1",
          "transcript_support_level": null,
          "aa_start": 866,
          "aa_end": null,
          "aa_length": 1327,
          "cds_start": 2597,
          "cds_end": null,
          "cds_length": 3984,
          "cdna_start": 2687,
          "cdna_end": null,
          "cdna_length": 4175,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 36,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.2531A>G",
          "hgvs_p": "p.Gln844Arg",
          "transcript": "XM_047443903.1",
          "protein_id": "XP_047299859.1",
          "transcript_support_level": null,
          "aa_start": 844,
          "aa_end": null,
          "aa_length": 1305,
          "cds_start": 2531,
          "cds_end": null,
          "cds_length": 3918,
          "cdna_start": 2621,
          "cdna_end": null,
          "cdna_length": 4109,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 10,
          "exon_rank_end": null,
          "exon_count": 34,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.1037A>G",
          "hgvs_p": "p.Gln346Arg",
          "transcript": "XM_011532759.3",
          "protein_id": "XP_011531061.1",
          "transcript_support_level": null,
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          "aa_length": 1229,
          "cds_start": 1037,
          "cds_end": null,
          "cds_length": 3690,
          "cdna_start": 1205,
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          "mane_select": null,
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        },
        {
          "aa_ref": "Q",
          "aa_alt": "R",
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          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 8,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": null,
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          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.734A>G",
          "hgvs_p": "p.Gln245Arg",
          "transcript": "XM_047443904.1",
          "protein_id": "XP_047299860.1",
          "transcript_support_level": null,
          "aa_start": 245,
          "aa_end": null,
          "aa_length": 1128,
          "cds_start": 734,
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          "cdna_start": 859,
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        },
        {
          "aa_ref": "Q",
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          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 7,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "c.662A>G",
          "hgvs_p": "p.Gln221Arg",
          "transcript": "XM_011532760.3",
          "protein_id": "XP_011531062.1",
          "transcript_support_level": null,
          "aa_start": 221,
          "aa_end": null,
          "aa_length": 1104,
          "cds_start": 662,
          "cds_end": null,
          "cds_length": 3315,
          "cdna_start": 917,
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          "cdna_length": 3625,
          "mane_select": null,
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          "feature": null
        },
        {
          "aa_ref": null,
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          "canonical": false,
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          "strand": false,
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          ],
          "exon_rank": 25,
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          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.2729A>G",
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          "transcript": "ENST00000507184.5",
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          "mane_select": null,
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          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
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          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_rank": 22,
          "exon_rank_end": null,
          "exon_count": 42,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*1770A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674701.1",
          "protein_id": "ENSP00000502275.1",
          "transcript_support_level": null,
          "aa_start": null,
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          "aa_length": null,
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          "cds_length": null,
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          "mane_select": null,
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          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
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          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_rank": 23,
          "exon_rank_end": null,
          "exon_count": 44,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*612A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674824.1",
          "protein_id": "ENSP00000501824.1",
          "transcript_support_level": null,
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          "cds_start": -4,
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          "cdna_start": null,
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          "cdna_length": 5391,
          "mane_select": null,
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          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
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          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_rank": 23,
          "exon_rank_end": null,
          "exon_count": 44,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*2194A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674932.1",
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        },
        {
          "aa_ref": null,
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          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_rank": 22,
          "exon_rank_end": null,
          "exon_count": 43,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.1916A>G",
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          "transcript": "ENST00000675410.1",
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          "cdna_start": null,
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          "mane_select": null,
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          "biotype": null,
          "feature": null
        },
        {
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          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 47,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*1887A>G",
          "hgvs_p": null,
          "transcript": "ENST00000676119.1",
          "protein_id": "ENSP00000501701.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": -4,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
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          "cdna_length": 5113,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_rank": 22,
          "exon_rank_end": null,
          "exon_count": 42,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*1770A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674701.1",
          "protein_id": "ENSP00000502275.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": -4,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 6271,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_rank": 23,
          "exon_rank_end": null,
          "exon_count": 44,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*612A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674824.1",
          "protein_id": "ENSP00000501824.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": -4,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5391,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_rank": 23,
          "exon_rank_end": null,
          "exon_count": 44,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*2194A>G",
          "hgvs_p": null,
          "transcript": "ENST00000674932.1",
          "protein_id": "ENSP00000501967.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": -4,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 6133,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_rank": 24,
          "exon_rank_end": null,
          "exon_count": 47,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "IFT172",
          "gene_hgnc_id": 30391,
          "hgvs_c": "n.*1887A>G",
          "hgvs_p": null,
          "transcript": "ENST00000676119.1",
          "protein_id": "ENSP00000501701.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": -4,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5113,
          "mane_select": null,
          "mane_plus": null,
          "biotype": null,
          "feature": null
        }
      ],
      "gene_symbol": "IFT172",
      "gene_hgnc_id": 30391,
      "dbsnp": "rs139229844",
      "frequency_reference_population": 0.00007252998,
      "hom_count_reference_population": 0,
      "allele_count_reference_population": 117,
      "gnomad_exomes_af": 0.0000342277,
      "gnomad_genomes_af": 0.000439863,
      "gnomad_exomes_ac": 50,
      "gnomad_genomes_ac": 67,
      "gnomad_exomes_homalt": 0,
      "gnomad_genomes_homalt": 0,
      "gnomad_mito_homoplasmic": null,
      "gnomad_mito_heteroplasmic": null,
      "computational_score_selected": 0.05695471167564392,
      "computational_prediction_selected": "Benign",
      "computational_source_selected": "MetaRNN",
      "splice_score_selected": 0,
      "splice_prediction_selected": "Benign",
      "splice_source_selected": "max_spliceai",
      "revel_score": 0.073,
      "revel_prediction": "Benign",
      "alphamissense_score": 0.0881,
      "alphamissense_prediction": "Benign",
      "bayesdelnoaf_score": -0.22,
      "bayesdelnoaf_prediction": "Benign",
      "phylop100way_score": 5.961,
      "phylop100way_prediction": "Uncertain_significance",
      "spliceai_max_score": 0,
      "spliceai_max_prediction": "Benign",
      "dbscsnv_ada_score": null,
      "dbscsnv_ada_prediction": null,
      "apogee2_score": null,
      "apogee2_prediction": null,
      "mitotip_score": null,
      "mitotip_prediction": null,
      "acmg_score": -9,
      "acmg_classification": "Benign",
      "acmg_criteria": "BP4_Strong,BP6,BS1",
      "acmg_by_gene": [
        {
          "score": -9,
          "benign_score": 9,
          "pathogenic_score": 0,
          "criteria": [
            "BP4_Strong",
            "BP6",
            "BS1"
          ],
          "verdict": "Benign",
          "transcript": "ENST00000260570.8",
          "gene_symbol": "IFT172",
          "hgnc_id": 30391,
          "effects": [
            "missense_variant"
          ],
          "inheritance_mode": "AR,AD",
          "hgvs_c": "c.2597A>G",
          "hgvs_p": "p.Gln866Arg"
        }
      ],
      "clinvar_disease": "Bardet-Biedl syndrome 20,IFT172-related disorder,Inborn genetic diseases,Retinitis pigmentosa 71,Short-rib thoracic dysplasia 10 with or without polydactyly,not provided",
      "clinvar_classification": "Conflicting classifications of pathogenicity",
      "clinvar_review_status": "criteria provided, conflicting classifications",
      "clinvar_submissions_summary": "US:2 LB:2",
      "phenotype_combined": "Inborn genetic diseases|Short-rib thoracic dysplasia 10 with or without polydactyly;Retinitis pigmentosa 71|not provided|Short-rib thoracic dysplasia 10 with or without polydactyly;Retinitis pigmentosa 71;Bardet-Biedl syndrome 20|IFT172-related disorder",
      "pathogenicity_classification_combined": "Conflicting classifications of pathogenicity",
      "custom_annotations": null
    }
  ],
  "message": null
}