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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 6-28331910-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=6&pos=28331910&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "6",
"pos": 28331910,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "ENST00000344279.11",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-95-2132G>A",
"hgvs_p": null,
"transcript": "NM_030899.5",
"protein_id": "NP_112161.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2812,
"mane_select": "ENST00000344279.11",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-95-2132G>A",
"hgvs_p": null,
"transcript": "ENST00000344279.11",
"protein_id": "ENSP00000345339.6",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2812,
"mane_select": "NM_030899.5",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "ENST00000396838.6",
"protein_id": "ENSP00000380050.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3176,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-95-2132G>A",
"hgvs_p": null,
"transcript": "ENST00000439158.5",
"protein_id": "ENSP00000413705.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3050,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-97+3920G>A",
"hgvs_p": null,
"transcript": "ENST00000446474.5",
"protein_id": "ENSP00000402937.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 247,
"cds_start": -4,
"cds_end": null,
"cds_length": 744,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2562,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "NM_001135215.1",
"protein_id": "NP_001128687.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3554,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-95-2132G>A",
"hgvs_p": null,
"transcript": "NM_001135216.1",
"protein_id": "NP_001128688.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3050,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "NM_001243241.1",
"protein_id": "NP_001230170.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2975,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "NM_145909.3",
"protein_id": "NP_665916.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3185,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "ENST00000414429.5",
"protein_id": "ENSP00000390076.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": -4,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
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"cdna_length": 3551,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-97+375G>A",
"hgvs_p": null,
"transcript": "NM_001243242.1",
"protein_id": "NP_001230171.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 3,
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-97+3920G>A",
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"transcript": "NM_001243243.1",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 3,
"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-97+4172G>A",
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"transcript": "NM_001243244.1",
"protein_id": "NP_001230173.1",
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},
{
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"strand": false,
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],
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"exon_count": 4,
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-97+375G>A",
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"transcript": "ENST00000611469.4",
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},
{
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],
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"gene_symbol": "ZSCAN31",
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"transcript": "ENST00000453745.5",
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},
{
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],
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-97+4172G>A",
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"transcript": "ENST00000435857.5",
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},
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],
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-31-2196G>A",
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"transcript": "ENST00000439636.5",
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},
{
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"strand": false,
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],
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"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
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"transcript": "ENST00000447021.1",
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},
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"strand": false,
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],
"exon_rank": null,
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"gene_symbol": "ZSCAN31",
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},
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],
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"gene_symbol": "ZSCAN31",
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},
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],
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"gene_symbol": "ZSCAN31",
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},
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.34-4377G>A",
"hgvs_p": null,
"transcript": "ENST00000426434.1",
"protein_id": "ENSP00000398680.1",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-31-2196G>A",
"hgvs_p": null,
"transcript": "ENST00000434036.5",
"protein_id": "ENSP00000416225.1",
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