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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 7-100613863-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=7&pos=100613863&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "7",
"pos": 100613863,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_023948.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "NM_023948.5",
"protein_id": "NP_076438.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1154,
"mane_select": "ENST00000393950.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_023948.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000393950.7",
"protein_id": "ENSP00000377522.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1154,
"mane_select": "NM_023948.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000393950.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.481+157G>C",
"hgvs_p": null,
"transcript": "ENST00000424091.2",
"protein_id": "ENSP00000404626.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 225,
"cds_start": null,
"cds_end": null,
"cds_length": 678,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1115,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000424091.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000921523.1",
"protein_id": "ENSP00000591582.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 258,
"cds_start": null,
"cds_end": null,
"cds_length": 777,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1178,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000921523.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.541+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902391.1",
"protein_id": "ENSP00000572450.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 245,
"cds_start": null,
"cds_end": null,
"cds_length": 738,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1121,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000902391.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.541+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902399.1",
"protein_id": "ENSP00000572458.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 245,
"cds_start": null,
"cds_end": null,
"cds_length": 738,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1172,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000902399.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "NM_001040097.2",
"protein_id": "NP_001035186.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1044,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001040097.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "NM_001040098.1",
"protein_id": "NP_001035187.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1020,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001040098.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "NM_001363415.1",
"protein_id": "NP_001350344.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1027,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363415.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "NM_001363416.1",
"protein_id": "NP_001350345.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1057,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363416.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000223054.8",
"protein_id": "ENSP00000223054.4",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
"cds_end": null,
"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1053,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000223054.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000379527.6",
"protein_id": "ENSP00000368842.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
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"cds_length": 708,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1016,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000379527.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902390.1",
"protein_id": "ENSP00000572449.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000902390.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
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"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902396.1",
"protein_id": "ENSP00000572455.1",
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000902396.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902397.1",
"protein_id": "ENSP00000572456.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 235,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000902397.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000921521.1",
"protein_id": "ENSP00000591580.1",
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000921521.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.481+157G>C",
"hgvs_p": null,
"transcript": "NM_001040099.2",
"protein_id": "NP_001035188.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 225,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": 1124,
"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001040099.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.481+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902392.1",
"protein_id": "ENSP00000572451.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 225,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000902392.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.481+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902393.1",
"protein_id": "ENSP00000572452.1",
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"biotype": "protein_coding",
"feature": "ENST00000902393.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.481+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902395.1",
"protein_id": "ENSP00000572454.1",
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"feature": "ENST00000902395.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000493970.5",
"protein_id": "ENSP00000417276.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 224,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": 853,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000493970.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "MOSPD3",
"gene_hgnc_id": 25078,
"hgvs_c": "c.511+157G>C",
"hgvs_p": null,
"transcript": "ENST00000902394.1",
"protein_id": "ENSP00000572453.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 180,
"cds_start": null,
"cds_end": null,
"cds_length": 543,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 846,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000902394.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
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}
],
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}