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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 7-14848793-C-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=7&pos=14848793&ref=C&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "7",
"pos": 14848793,
"ref": "C",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000402815.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350709.2",
"protein_id": "NP_001337638.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 803,
"cds_start": -4,
"cds_end": null,
"cds_length": 2412,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6841,
"mane_select": "ENST00000402815.6",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "ENST00000402815.6",
"protein_id": "ENSP00000384909.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 803,
"cds_start": -4,
"cds_end": null,
"cds_length": 2412,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6841,
"mane_select": "NM_001350709.2",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350705.1",
"protein_id": "NP_001337634.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 804,
"cds_start": -4,
"cds_end": null,
"cds_length": 2415,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7212,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350706.2",
"protein_id": "NP_001337635.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 804,
"cds_start": -4,
"cds_end": null,
"cds_length": 2415,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6844,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "ENST00000403951.6",
"protein_id": "ENSP00000385780.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 804,
"cds_start": -4,
"cds_end": null,
"cds_length": 2415,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6917,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350707.2",
"protein_id": "NP_001337636.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 803,
"cds_start": -4,
"cds_end": null,
"cds_length": 2412,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6844,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350708.1",
"protein_id": "NP_001337637.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 803,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 7209,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350715.1",
"protein_id": "NP_001337644.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 797,
"cds_start": -4,
"cds_end": null,
"cds_length": 2394,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7191,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "DGKB",
"gene_hgnc_id": 2850,
"hgvs_c": "c.-187-7343G>C",
"hgvs_p": null,
"transcript": "NM_001350716.2",
"protein_id": "NP_001337645.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 797,
"cds_start": -4,
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"cds_length": 2394,
"cdna_start": null,
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"cdna_length": 6823,
"mane_select": null,
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"feature": null
},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"gene_symbol": "DGKB",
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"hgvs_c": "c.-187-7343G>C",
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"transcript": "NM_001350711.2",
"protein_id": "NP_001337640.1",
"transcript_support_level": null,
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"gene_symbol": "DGKB",
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"hgvs_c": "c.-187-7343G>C",
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"transcript": "NM_001350712.1",
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},
{
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],
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},
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],
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},
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],
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],
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},
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],
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"transcript": "NM_001350721.2",
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],
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"gene_symbol": "DGKB",
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"hgvs_c": "c.-187-7343G>C",
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"transcript": "ENST00000437998.1",
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},
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],
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"gene_symbol": "DGKB",
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"hgvs_c": "n.409-7343G>C",
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}