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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 8-2129084-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=8&pos=2129084&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "8",
"pos": 2129084,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_003970.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "NM_003970.4",
"protein_id": "NP_003961.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000262113.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_003970.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000262113.9",
"protein_id": "ENSP00000262113.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_003970.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000262113.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 38,
"intron_rank": 32,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3788-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887732.1",
"protein_id": "ENSP00000557791.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1496,
"cds_start": null,
"cds_end": null,
"cds_length": 4491,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887732.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 38,
"intron_rank": 32,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3776-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887733.1",
"protein_id": "ENSP00000557792.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1492,
"cds_start": null,
"cds_end": null,
"cds_length": 4479,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887733.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 38,
"intron_rank": 32,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3776-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953568.1",
"protein_id": "ENSP00000623627.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1492,
"cds_start": null,
"cds_end": null,
"cds_length": 4479,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953568.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 38,
"intron_rank": 32,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3749-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953575.1",
"protein_id": "ENSP00000623634.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1483,
"cds_start": null,
"cds_end": null,
"cds_length": 4452,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953575.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3737-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953574.1",
"protein_id": "ENSP00000623633.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1479,
"cds_start": null,
"cds_end": null,
"cds_length": 4440,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953574.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887731.1",
"protein_id": "ENSP00000557790.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887731.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887736.1",
"protein_id": "ENSP00000557795.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887736.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953567.1",
"protein_id": "ENSP00000623626.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953567.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 38,
"intron_rank": 32,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953572.1",
"protein_id": "ENSP00000623631.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
"cds_end": null,
"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953572.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953573.1",
"protein_id": "ENSP00000623632.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
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"cds_length": 4398,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953573.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953580.1",
"protein_id": "ENSP00000623639.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953580.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 36,
"intron_rank": 30,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953581.1",
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"cdna_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953581.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953582.1",
"protein_id": "ENSP00000623641.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1465,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953582.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3668-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887734.1",
"protein_id": "ENSP00000557793.1",
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"cdna_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887734.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3653-43G>C",
"hgvs_p": null,
"transcript": "ENST00000887735.1",
"protein_id": "ENSP00000557794.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cds_length": 4356,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887735.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 36,
"intron_rank": 30,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3650-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953577.1",
"protein_id": "ENSP00000623636.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1450,
"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000953577.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 37,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3599-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953569.1",
"protein_id": "ENSP00000623628.1",
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},
{
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 35,
"intron_rank": 31,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3695-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953576.1",
"protein_id": "ENSP00000623635.1",
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"feature": "ENST00000953576.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
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"intron_rank": 30,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3479-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953579.1",
"protein_id": "ENSP00000623638.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1393,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953579.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 26,
"intron_rank_end": null,
"gene_symbol": "MYOM2",
"gene_hgnc_id": 7614,
"hgvs_c": "c.3134-43G>C",
"hgvs_p": null,
"transcript": "ENST00000953570.1",
"protein_id": "ENSP00000623629.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1278,
"cds_start": null,
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"cds_length": 3837,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953570.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
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}
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}