← Back to variant description
GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 9-110875574-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=9&pos=110875574&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "9",
"pos": 110875574,
"ref": "G",
"alt": "A",
"effect": "synonymous_variant",
"transcript": "ENST00000683809.1",
"consequences": [
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351411.2",
"protein_id": "NP_001338340.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1507,
"cdna_end": null,
"cdna_length": 3818,
"mane_select": "ENST00000683809.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "ENST00000683809.1",
"protein_id": "ENSP00000506912.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1507,
"cdna_end": null,
"cdna_length": 3818,
"mane_select": "NM_001351411.2",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "ENST00000374430.6",
"protein_id": "ENSP00000363552.1",
"transcript_support_level": 1,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1197,
"cdna_end": null,
"cdna_length": 2993,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "ENST00000374431.7",
"protein_id": "ENSP00000363553.3",
"transcript_support_level": 1,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1326,
"cdna_end": null,
"cdna_length": 3637,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351397.2",
"protein_id": "NP_001338326.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1252,
"cdna_end": null,
"cdna_length": 3563,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351398.2",
"protein_id": "NP_001338327.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1449,
"cdna_end": null,
"cdna_length": 3760,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351399.2",
"protein_id": "NP_001338328.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1395,
"cdna_end": null,
"cdna_length": 3706,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351400.2",
"protein_id": "NP_001338329.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1409,
"cdna_end": null,
"cdna_length": 3720,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351401.2",
"protein_id": "NP_001338330.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1435,
"cdna_end": null,
"cdna_length": 3746,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351402.2",
"protein_id": "NP_001338331.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1355,
"cdna_end": null,
"cdna_length": 3666,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351403.2",
"protein_id": "NP_001338332.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1212,
"cdna_end": null,
"cdna_length": 3523,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351404.2",
"protein_id": "NP_001338333.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1292,
"cdna_end": null,
"cdna_length": 3603,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351405.2",
"protein_id": "NP_001338334.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1300,
"cdna_end": null,
"cdna_length": 3611,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351406.2",
"protein_id": "NP_001338335.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1427,
"cdna_end": null,
"cdna_length": 3738,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351407.2",
"protein_id": "NP_001338336.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1624,
"cdna_end": null,
"cdna_length": 3935,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351408.2",
"protein_id": "NP_001338337.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1570,
"cdna_end": null,
"cdna_length": 3881,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351409.2",
"protein_id": "NP_001338338.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1650,
"cdna_end": null,
"cdna_length": 3961,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351410.2",
"protein_id": "NP_001338339.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1658,
"cdna_end": null,
"cdna_length": 3969,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351412.2",
"protein_id": "NP_001338341.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1615,
"cdna_end": null,
"cdna_length": 3926,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351413.2",
"protein_id": "NP_001338342.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1623,
"cdna_end": null,
"cdna_length": 3934,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351414.2",
"protein_id": "NP_001338343.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1515,
"cdna_end": null,
"cdna_length": 3826,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351415.2",
"protein_id": "NP_001338344.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1567,
"cdna_end": null,
"cdna_length": 3878,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351416.2",
"protein_id": "NP_001338345.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1513,
"cdna_end": null,
"cdna_length": 3824,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351417.2",
"protein_id": "NP_001338346.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1450,
"cdna_end": null,
"cdna_length": 3761,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351418.2",
"protein_id": "NP_001338347.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1558,
"cdna_end": null,
"cdna_length": 3869,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351419.2",
"protein_id": "NP_001338348.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1351,
"cdna_end": null,
"cdna_length": 3662,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001351420.2",
"protein_id": "NP_001338349.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1396,
"cdna_end": null,
"cdna_length": 3707,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387470.1",
"protein_id": "NP_001374399.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1340,
"cdna_end": null,
"cdna_length": 3651,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387471.1",
"protein_id": "NP_001374400.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1174,
"cdna_end": null,
"cdna_length": 3485,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387472.1",
"protein_id": "NP_001374401.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1332,
"cdna_end": null,
"cdna_length": 3643,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387473.1",
"protein_id": "NP_001374402.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1524,
"cdna_end": null,
"cdna_length": 3835,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387474.1",
"protein_id": "NP_001374403.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1470,
"cdna_end": null,
"cdna_length": 3781,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387475.1",
"protein_id": "NP_001374404.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1327,
"cdna_end": null,
"cdna_length": 3638,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387476.1",
"protein_id": "NP_001374405.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1415,
"cdna_end": null,
"cdna_length": 3726,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387477.1",
"protein_id": "NP_001374406.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1400,
"cdna_end": null,
"cdna_length": 3711,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387478.1",
"protein_id": "NP_001374407.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1430,
"cdna_end": null,
"cdna_length": 3741,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387479.1",
"protein_id": "NP_001374408.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1489,
"cdna_end": null,
"cdna_length": 3800,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387480.1",
"protein_id": "NP_001374409.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1341,
"cdna_end": null,
"cdna_length": 3652,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387481.1",
"protein_id": "NP_001374410.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1209,
"cdna_end": null,
"cdna_length": 3520,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387482.1",
"protein_id": "NP_001374411.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1214,
"cdna_end": null,
"cdna_length": 3525,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387483.1",
"protein_id": "NP_001374412.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1484,
"cdna_end": null,
"cdna_length": 3795,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387484.1",
"protein_id": "NP_001374413.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1564,
"cdna_end": null,
"cdna_length": 3875,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387485.1",
"protein_id": "NP_001374414.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1134,
"cdna_end": null,
"cdna_length": 3445,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387486.1",
"protein_id": "NP_001374415.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1287,
"cdna_end": null,
"cdna_length": 3598,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387487.1",
"protein_id": "NP_001374416.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1502,
"cdna_end": null,
"cdna_length": 3813,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387488.1",
"protein_id": "NP_001374417.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1429,
"cdna_end": null,
"cdna_length": 3740,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387489.1",
"protein_id": "NP_001374418.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1590,
"cdna_end": null,
"cdna_length": 3901,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387490.1",
"protein_id": "NP_001374419.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1704,
"cdna_end": null,
"cdna_length": 4015,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387491.1",
"protein_id": "NP_001374420.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1561,
"cdna_end": null,
"cdna_length": 3872,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387492.1",
"protein_id": "NP_001374421.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1699,
"cdna_end": null,
"cdna_length": 4010,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387493.1",
"protein_id": "NP_001374422.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1424,
"cdna_end": null,
"cdna_length": 3735,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387494.1",
"protein_id": "NP_001374423.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1779,
"cdna_end": null,
"cdna_length": 4090,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387495.1",
"protein_id": "NP_001374424.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1582,
"cdna_end": null,
"cdna_length": 3893,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387496.1",
"protein_id": "NP_001374425.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1569,
"cdna_end": null,
"cdna_length": 3880,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387497.1",
"protein_id": "NP_001374426.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1349,
"cdna_end": null,
"cdna_length": 3660,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387498.1",
"protein_id": "NP_001374427.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1645,
"cdna_end": null,
"cdna_length": 3956,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387501.1",
"protein_id": "NP_001374430.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1647,
"cdna_end": null,
"cdna_length": 3958,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387502.1",
"protein_id": "NP_001374431.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1458,
"cdna_end": null,
"cdna_length": 3769,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387503.1",
"protein_id": "NP_001374432.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1367,
"cdna_end": null,
"cdna_length": 3678,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387504.1",
"protein_id": "NP_001374433.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1435,
"cdna_end": null,
"cdna_length": 3746,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387505.1",
"protein_id": "NP_001374434.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1593,
"cdna_end": null,
"cdna_length": 3904,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387506.1",
"protein_id": "NP_001374435.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1525,
"cdna_end": null,
"cdna_length": 3836,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387507.1",
"protein_id": "NP_001374436.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1533,
"cdna_end": null,
"cdna_length": 3844,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387508.1",
"protein_id": "NP_001374437.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1588,
"cdna_end": null,
"cdna_length": 3899,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387509.1",
"protein_id": "NP_001374438.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1579,
"cdna_end": null,
"cdna_length": 3890,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387510.1",
"protein_id": "NP_001374439.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1445,
"cdna_end": null,
"cdna_length": 3756,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387511.1",
"protein_id": "NP_001374440.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1504,
"cdna_end": null,
"cdna_length": 3815,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387512.1",
"protein_id": "NP_001374441.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1622,
"cdna_end": null,
"cdna_length": 3933,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387513.1",
"protein_id": "NP_001374442.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1593,
"cdna_end": null,
"cdna_length": 3904,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387514.1",
"protein_id": "NP_001374443.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1124,
"cdna_end": null,
"cdna_length": 3435,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001387515.1",
"protein_id": "NP_001374444.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1202,
"cdna_end": null,
"cdna_length": 3513,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_001401.5",
"protein_id": "NP_001392.2",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1292,
"cdna_end": null,
"cdna_length": 3603,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "NM_057159.4",
"protein_id": "NP_476500.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1370,
"cdna_end": null,
"cdna_length": 3681,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "ENST00000358883.8",
"protein_id": "ENSP00000351755.4",
"transcript_support_level": 2,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1290,
"cdna_end": null,
"cdna_length": 2687,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.888C>T",
"hgvs_p": "p.Arg296Arg",
"transcript": "NM_001387516.1",
"protein_id": "NP_001374445.1",
"transcript_support_level": null,
"aa_start": 296,
"aa_end": null,
"aa_length": 346,
"cds_start": 888,
"cds_end": null,
"cds_length": 1041,
"cdna_start": 1342,
"cdna_end": null,
"cdna_length": 3653,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.888C>T",
"hgvs_p": "p.Arg296Arg",
"transcript": "NM_001387517.1",
"protein_id": "NP_001374446.1",
"transcript_support_level": null,
"aa_start": 296,
"aa_end": null,
"aa_length": 346,
"cds_start": 888,
"cds_end": null,
"cds_length": 1041,
"cdna_start": 1572,
"cdna_end": null,
"cdna_length": 3883,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.888C>T",
"hgvs_p": "p.Arg296Arg",
"transcript": "NM_001387518.1",
"protein_id": "NP_001374447.1",
"transcript_support_level": null,
"aa_start": 296,
"aa_end": null,
"aa_length": 346,
"cds_start": 888,
"cds_end": null,
"cds_length": 1041,
"cdna_start": 1195,
"cdna_end": null,
"cdna_length": 3506,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "R",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg",
"transcript": "XM_047422903.1",
"protein_id": "XP_047278859.1",
"transcript_support_level": null,
"aa_start": 314,
"aa_end": null,
"aa_length": 364,
"cds_start": 942,
"cds_end": null,
"cds_length": 1095,
"cdna_start": 1508,
"cdna_end": null,
"cdna_length": 3819,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
}
],
"gene_symbol": "LPAR1",
"gene_hgnc_id": 3166,
"dbsnp": "rs3739709",
"frequency_reference_population": 0.17964391,
"hom_count_reference_population": 27371,
"allele_count_reference_population": 289886,
"gnomad_exomes_af": 0.183072,
"gnomad_genomes_af": 0.146681,
"gnomad_exomes_ac": 267592,
"gnomad_genomes_ac": 22294,
"gnomad_exomes_homalt": 25361,
"gnomad_genomes_homalt": 2010,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": -0.7099999785423279,
"computational_prediction_selected": "Benign",
"computational_source_selected": "BayesDel_noAF",
"splice_score_selected": 0,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": null,
"revel_prediction": null,
"alphamissense_score": null,
"alphamissense_prediction": null,
"bayesdelnoaf_score": -0.71,
"bayesdelnoaf_prediction": "Benign",
"phylop100way_score": -1.455,
"phylop100way_prediction": "Benign",
"spliceai_max_score": 0,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": -13,
"acmg_classification": "Benign",
"acmg_criteria": "BP4_Strong,BP7,BA1",
"acmg_by_gene": [
{
"score": -13,
"benign_score": 13,
"pathogenic_score": 0,
"criteria": [
"BP4_Strong",
"BP7",
"BA1"
],
"verdict": "Benign",
"transcript": "ENST00000683809.1",
"gene_symbol": "LPAR1",
"hgnc_id": 3166,
"effects": [
"synonymous_variant"
],
"inheritance_mode": "AD",
"hgvs_c": "c.942C>T",
"hgvs_p": "p.Arg314Arg"
}
],
"clinvar_disease": "",
"clinvar_classification": "",
"clinvar_review_status": "",
"clinvar_submissions_summary": "",
"phenotype_combined": null,
"pathogenicity_classification_combined": null,
"custom_annotations": null
}
],
"message": null
}