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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 9-5807444-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=9&pos=5807444&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "9",
"pos": 5807444,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "ENST00000339450.10",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "NM_024896.3",
"protein_id": "NP_079172.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 904,
"cds_start": -4,
"cds_end": null,
"cds_length": 2715,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5377,
"mane_select": "ENST00000339450.10",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000339450.10",
"protein_id": "ENSP00000340427.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 904,
"cds_start": -4,
"cds_end": null,
"cds_length": 2715,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5377,
"mane_select": "NM_024896.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.975-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000214893.10",
"protein_id": null,
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4724,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000489219.5",
"protein_id": "ENSP00000417474.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3293,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000688887.1",
"protein_id": "ENSP00000510241.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 900,
"cds_start": -4,
"cds_end": null,
"cds_length": 2703,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4310,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000689030.1",
"protein_id": "ENSP00000508877.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 900,
"cds_start": -4,
"cds_end": null,
"cds_length": 2703,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3277,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000693487.1",
"protein_id": "ENSP00000509985.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 896,
"cds_start": -4,
"cds_end": null,
"cds_length": 2691,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3106,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000693638.1",
"protein_id": "ENSP00000509499.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 880,
"cds_start": -4,
"cds_end": null,
"cds_length": 2643,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4868,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1462-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000691560.1",
"protein_id": "ENSP00000510453.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 875,
"cds_start": -4,
"cds_end": null,
"cds_length": 2628,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5211,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1456-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000686418.1",
"protein_id": "ENSP00000508417.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 873,
"cds_start": -4,
"cds_end": null,
"cds_length": 2622,
"cdna_start": null,
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"cdna_length": 5295,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1548+2567A>G",
"hgvs_p": null,
"transcript": "NM_001410952.1",
"protein_id": "NP_001397881.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 782,
"cds_start": -4,
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"cds_length": 2349,
"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 8,
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"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1548+2567A>G",
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"transcript": "ENST00000691251.1",
"protein_id": "ENSP00000508900.1",
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"cdna_start": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "c.1314+2567A>G",
"hgvs_p": null,
"transcript": "ENST00000690648.1",
"protein_id": "ENSP00000510403.1",
"transcript_support_level": null,
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},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 16,
"intron_rank": 8,
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"gene_symbol": "ERMP1",
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"hgvs_c": "n.1549-1659A>G",
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"transcript": "ENST00000462592.5",
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},
{
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],
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"gene_symbol": "ERMP1",
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"hgvs_c": "n.1549-1659A>G",
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"transcript": "ENST00000487088.6",
"protein_id": "ENSP00000432986.2",
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"aa_start": null,
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"feature": null
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 6,
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"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.*738-1659A>G",
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"transcript": "ENST00000684950.1",
"protein_id": "ENSP00000508646.1",
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},
{
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],
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"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.*743-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000685462.1",
"protein_id": "ENSP00000509701.1",
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"feature": null
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 16,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000688202.1",
"protein_id": "ENSP00000510190.1",
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},
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 14,
"intron_rank": 8,
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"gene_symbol": "ERMP1",
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"hgvs_c": "n.1549-1659A>G",
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"transcript": "ENST00000688899.1",
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},
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],
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"intron_rank": 6,
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"gene_symbol": "ERMP1",
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},
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],
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"gene_symbol": "ERMP1",
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"hgvs_c": "n.1549-1659A>G",
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},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 16,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.1549-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000689364.1",
"protein_id": "ENSP00000509092.1",
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"mane_select": null,
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"feature": null
},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "ERMP1",
"gene_hgnc_id": 23703,
"hgvs_c": "n.*1199-1659A>G",
"hgvs_p": null,
"transcript": "ENST00000689671.1",
"protein_id": "ENSP00000509042.1",
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}