PDE7B-AS1

PDE7B antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 6:135991936-136225751

Links

ENSG00000237596 ∙ NCBI:644135 ∙ ∙ HGNC:56334 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the PDE7B-AS1 gene.

• Inborn genetic diseases (9 variants)
• not provided (5 variants)
• Malignant tumor of prostate (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the PDE7B-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			10		5	15
Total	0	0	10	0	5

Variants in PDE7B-AS1

This is a list of pathogenic ClinVar variants found in the PDE7B-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-136108803-G-A		not specified	Uncertain significance (May 11, 2022)
6-136147433-G-A			Benign (Jun 27, 2018)
6-136149088-A-G		not specified	Uncertain significance (Oct 26, 2021)
6-136154165-A-C		not specified	Uncertain significance (Jan 10, 2023)
6-136155644-G-A			Benign (Dec 14, 2017)
6-136155659-G-A		not specified	Uncertain significance (Jan 08, 2024)
6-136155723-A-G		not specified	Uncertain significance (Apr 18, 2023)
6-136173827-C-T		Malignant tumor of prostate	Uncertain significance (-)
6-136173836-A-G		not specified	Uncertain significance (Jul 14, 2021)
6-136173860-C-G		not specified	Uncertain significance (Jul 17, 2023)
6-136173871-T-C			Benign (Aug 20, 2018)
6-136179071-G-C		not specified	Uncertain significance (Feb 06, 2023)
6-136179077-A-G			Benign (Jun 27, 2018)
6-136181230-G-A		not specified	Uncertain significance (Jun 18, 2024)
6-136181230-G-T		not specified	Uncertain significance (Oct 05, 2023)
6-136181267-T-G		not specified	Uncertain significance (Jul 19, 2022)
6-136181305-G-C		not specified	Uncertain significance (Dec 28, 2023)
6-136187075-T-C		not specified	Uncertain significance (Dec 06, 2022)
6-136191773-G-A		not specified	Uncertain significance (Nov 17, 2022)
6-136191810-G-C		not specified	Uncertain significance (Dec 08, 2023)
6-136191833-G-A		not specified	Uncertain significance (Sep 20, 2023)
6-136191834-C-G			Benign (May 14, 2018)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP