GeneBe

SIGLEC10-AS2

SIGLEC10 antisense RNA 2, the group of Antisense RNAs

Basic information

Region (hg38): 19:51414298-51414965

Links

ENSG00000254760 ∙ ∙ ∙ HGNC:40718 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SIGLEC10-AS2 gene.

  • Inborn genetic diseases (2 variants)
  • not provided (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SIGLEC10-AS2 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type Pathogenic Likely pathogenic VUS Likely benign Benign Sum
synonymous
0
missense
0
nonsense
0
start loss
0
frameshift
0
inframe indel
0
splice donor/acceptor (+/-2bp)
0
splice region
0
non coding
2
clinvar
1
clinvar
 3
Total 0 0 2 0 1

Variants in SIGLEC10-AS2

This is a list of pathogenic ClinVar variants found in the SIGLEC10-AS2 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position Type Phenotype Significance ClinVar
19-51414447-G-A not specified Uncertain significance (Jun 10, 2024)3318480
19-51414480-C-T not specified Uncertain significance (Jun 06, 2023)2558158
19-51414494-G-A not specified Uncertain significance (Sep 11, 2024)2387416
19-51414834-C-G Benign (Jul 26, 2017)770811
19-51414838-A-T not specified Uncertain significance (Dec 05, 2024)3441827
19-51414859-T-C not specified Uncertain significance (Nov 24, 2024)3441822
19-51414941-C-T not specified Uncertain significance (Oct 04, 2024)3441816
19-51414959-C-T not specified Uncertain significance (Nov 21, 2024)3441826

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP