SOCS3-DT

SOCS3 divergent transcript, the group of Divergent transcripts

Basic information

Region (hg38): 17:78357451-78374619

Links

ENSG00000266970 ∙ NCBI:101928674 ∙ ∙ HGNC:52799 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SOCS3-DT gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SOCS3-DT gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in SOCS3-DT

This is a list of pathogenic ClinVar variants found in the SOCS3-DT region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
17-78358464-G-A		not specified	Uncertain significance (Mar 11, 2024)
17-78358474-T-A		not specified	Uncertain significance (May 15, 2023)
17-78358485-T-C		not specified	Uncertain significance (Jun 26, 2023)
17-78358507-C-T		not specified	Uncertain significance (Jan 21, 2025)
17-78358654-G-A		not specified	Uncertain significance (Nov 09, 2023)
17-78358665-G-A		not specified	Uncertain significance (May 03, 2023)
17-78358675-T-C		not specified	Uncertain significance (Jan 31, 2023)
17-78358688-G-T		not specified	Benign (May 04, 2022)
17-78358758-G-A		not specified	Uncertain significance (Apr 08, 2024)
17-78358773-G-A		not specified	Uncertain significance (Apr 09, 2024)
17-78358833-G-C		not specified	Uncertain significance (Aug 20, 2024)
17-78358948-C-T		not specified	Uncertain significance (Mar 30, 2024)
17-78358968-T-C		not specified	Uncertain significance (Oct 03, 2022)
17-78358971-T-C		not specified	Uncertain significance (Oct 06, 2021)
17-78358987-C-T		not specified	Uncertain significance (Mar 30, 2024)
17-78359019-C-T		not specified	Uncertain significance (May 13, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP