TRDC

T cell receptor delta constant, the group of T cell receptor delta locus at 14q11.2

Basic information

Region (hg38): 14:22462932-22465787

Links

ENSG00000211829NCBI:28526OMIM:186810HGNC:12253Uniprot:B7Z8K6AlphaFoldGenCCjaxSfariGnomADPubmedClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TRDC gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TRDC gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type Pathogenic Likely pathogenic VUS Likely benign Benign Sum
synonymous
0
missense
0
nonsense
0
start loss
0
frameshift
0
inframe indel
0
splice donor/acceptor (+/-2bp)
0
splice region
0
non coding
0
Total 0 0 0 0 0

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Gene ontology

Biological process
phagocytosis, recognition;phagocytosis, engulfment;complement activation, classical pathway;defense response to bacterium;innate immune response;B cell receptor signaling pathway;positive regulation of B cell activation
Cellular component
external side of plasma membrane;integral component of membrane;immunoglobulin complex, circulating
Molecular function
antigen binding;immunoglobulin receptor binding