ZC3H11B

zinc finger CCCH-type containing 11B, the group of Zinc fingers CCCH-type

Basic information

Region (hg38): 1:219608011-219613105

Previous symbols: [ "ZC3HDC11B" ]

Links

ENSG00000215817

∙ NCBI:643136 ∙ ∙ HGNC:25659 ∙ Uniprot:A0A1B0GTU1 ∙ AlphaFold ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the ZC3H11B gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the ZC3H11B gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous				1 clinvar		1
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	1	0

Variants in ZC3H11B

This is a list of pathogenic ClinVar variants found in the ZC3H11B region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
1-219609933-A-G			Likely benign (Feb 01, 2023)	2639904

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Function: FUNCTION: May play a role in mRNA transport. {ECO:0000305}.;

Gene ontology

Biological process: poly(A)+ mRNA export from nucleus
Cellular component: transcription export complex
Molecular function: mRNA binding;metal ion binding