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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 1-16044378-C-CACACACACACACACACACACACACACACACAT (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=1&pos=16044378&ref=C&alt=CACACACACACACACACACACACACACACACAT&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "1",
"pos": 16044378,
"ref": "C",
"alt": "CACACACACACACACACACACACACACACACAT",
"effect": "intron_variant",
"transcript": "NM_000085.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "NM_000085.5",
"protein_id": "NP_000076.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 687,
"cds_start": null,
"cds_end": null,
"cds_length": 2064,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000375679.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_000085.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000375679.9",
"protein_id": "ENSP00000364831.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 687,
"cds_start": null,
"cds_end": null,
"cds_length": 2064,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_000085.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000375679.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"5_prime_UTR_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-115_-114insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906274.1",
"protein_id": "ENSP00000576333.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 686,
"cds_start": null,
"cds_end": null,
"cds_length": 2061,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906274.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906263.1",
"protein_id": "ENSP00000576322.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 705,
"cds_start": null,
"cds_end": null,
"cds_length": 2118,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906263.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906270.1",
"protein_id": "ENSP00000576329.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 704,
"cds_start": null,
"cds_end": null,
"cds_length": 2115,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906270.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906271.1",
"protein_id": "ENSP00000576330.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 694,
"cds_start": null,
"cds_end": null,
"cds_length": 2085,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906271.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906265.1",
"protein_id": "ENSP00000576324.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 693,
"cds_start": null,
"cds_end": null,
"cds_length": 2082,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906265.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CLCNKB",
"gene_hgnc_id": 2027,
"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906262.1",
"protein_id": "ENSP00000576321.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 692,
"cds_start": null,
"cds_end": null,
"cds_length": 2079,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000906262.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
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"gene_symbol": "CLCNKB",
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"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
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"transcript": "ENST00000906261.1",
"protein_id": "ENSP00000576320.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
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},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 20,
"intron_rank": 1,
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"gene_symbol": "CLCNKB",
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"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
"hgvs_p": null,
"transcript": "ENST00000906268.1",
"protein_id": "ENSP00000576327.1",
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},
{
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"consequences": [
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],
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"exon_count": 22,
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"gene_symbol": "CLCNKB",
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"hgvs_c": "c.-7-108_-7-107insACACACACACACACACACACACACACACACAT",
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"transcript": "ENST00000682338.1",
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},
{
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],
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},
{
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],
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},
{
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],
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},
{
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],
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},
{
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},
{
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],
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},
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],
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},
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],
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},
{
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],
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"gene_symbol": "CLCNKB",
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},
{
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}
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"message": null
}