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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 1-23028384-T-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=1&pos=23028384&ref=T&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "1",
"pos": 23028384,
"ref": "T",
"alt": "A",
"effect": "intron_variant",
"transcript": "ENST00000400181.9",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "NM_001009999.3",
"protein_id": "NP_001009999.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 876,
"cds_start": -4,
"cds_end": null,
"cds_length": 2631,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3085,
"mane_select": "ENST00000400181.9",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000400181.9",
"protein_id": "ENSP00000383042.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 876,
"cds_start": -4,
"cds_end": null,
"cds_length": 2631,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3085,
"mane_select": "NM_001009999.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000356634.7",
"protein_id": "ENSP00000349049.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 852,
"cds_start": -4,
"cds_end": null,
"cds_length": 2559,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3033,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "NM_001410762.1",
"protein_id": "NP_001397691.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 878,
"cds_start": -4,
"cds_end": null,
"cds_length": 2637,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3091,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000685102.1",
"protein_id": "ENSP00000509257.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 878,
"cds_start": -4,
"cds_end": null,
"cds_length": 2637,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3099,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "NM_001363654.2",
"protein_id": "NP_001350583.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 858,
"cds_start": -4,
"cds_end": null,
"cds_length": 2577,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3031,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000465864.2",
"protein_id": "ENSP00000473297.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 858,
"cds_start": -4,
"cds_end": null,
"cds_length": 2577,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3039,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "NM_015013.4",
"protein_id": "NP_055828.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 852,
"cds_start": -4,
"cds_end": null,
"cds_length": 2559,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3013,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000691404.1",
"protein_id": "ENSP00000509252.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 840,
"cds_start": -4,
"cds_end": null,
"cds_length": 2523,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3853,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "ENST00000692975.1",
"protein_id": "ENSP00000509892.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 820,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 3793,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
"hgvs_p": null,
"transcript": "NM_001410763.1",
"protein_id": "NP_001397692.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000691682.1",
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},
{
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 18,
"intron_rank": 1,
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"gene_symbol": "KDM1A",
"gene_hgnc_id": 29079,
"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000690627.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000692853.1",
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},
{
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"strand": true,
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],
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"gene_symbol": "KDM1A",
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"transcript": "ENST00000686771.1",
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},
{
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"consequences": [
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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},
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],
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000692056.1",
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},
{
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"strand": true,
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],
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"exon_count": 16,
"intron_rank": 1,
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000692209.1",
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},
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"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "KDM1A",
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},
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],
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"gene_symbol": "KDM1A",
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},
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],
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},
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"strand": true,
"consequences": [
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],
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"intron_rank": 1,
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"gene_symbol": "KDM1A",
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"hgvs_c": "c.352-2085T>A",
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"transcript": "ENST00000691694.1",
"protein_id": "ENSP00000509771.1",
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 2,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ENSG00000240553",
"gene_hgnc_id": null,
"hgvs_c": "n.262-7833A>T",
"hgvs_p": null,
"transcript": "ENST00000427154.1",
"protein_id": null,
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