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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 1-40754047-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=1&pos=40754047&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "1",
"pos": 40754047,
"ref": "G",
"alt": "A",
"effect": "intron_variant",
"transcript": "NM_014223.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "NM_014223.5",
"protein_id": "NP_055038.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 335,
"cds_start": -4,
"cds_end": null,
"cds_length": 1008,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1955,
"mane_select": "ENST00000447388.8",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000447388.8",
"protein_id": "ENSP00000404427.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 335,
"cds_start": -4,
"cds_end": null,
"cds_length": 1008,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1955,
"mane_select": "NM_014223.5",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000308733.9",
"protein_id": "ENSP00000312617.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 458,
"cds_start": -4,
"cds_end": null,
"cds_length": 1377,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2158,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000372654.5",
"protein_id": "ENSP00000361738.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 335,
"cds_start": -4,
"cds_end": null,
"cds_length": 1008,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1455,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000456393.6",
"protein_id": "ENSP00000408867.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 334,
"cds_start": -4,
"cds_end": null,
"cds_length": 1005,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1911,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "NM_001308114.1",
"protein_id": "NP_001295043.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 458,
"cds_start": -4,
"cds_end": null,
"cds_length": 1377,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2160,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "NM_001308115.2",
"protein_id": "NP_001295044.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 439,
"cds_start": -4,
"cds_end": null,
"cds_length": 1320,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2354,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000372652.5",
"protein_id": "ENSP00000361736.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 439,
"cds_start": -4,
"cds_end": null,
"cds_length": 1320,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2363,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "NM_001142588.2",
"protein_id": "NP_001136060.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 354,
"cds_start": -4,
"cds_end": null,
"cds_length": 1065,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2012,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 5,
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"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000425457.6",
"protein_id": "ENSP00000396620.2",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 354,
"cds_start": -4,
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"cds_length": 1065,
"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
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"gene_symbol": "NFYC",
"gene_hgnc_id": 7806,
"hgvs_c": "c.387+801G>A",
"hgvs_p": null,
"transcript": "ENST00000372651.5",
"protein_id": "ENSP00000361734.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "NFYC",
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"hgvs_c": "c.387+801G>A",
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"transcript": "ENST00000440226.7",
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},
{
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],
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"gene_symbol": "NFYC",
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"hgvs_c": "c.387+801G>A",
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"transcript": "NM_001142587.2",
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},
{
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],
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"gene_symbol": "NFYC",
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"hgvs_c": "c.387+801G>A",
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"transcript": "ENST00000372669.8",
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},
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],
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},
{
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"consequences": [
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],
"exon_rank": null,
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"intron_rank": 10,
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"gene_symbol": "NFYC",
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"hgvs_c": "c.387+801G>A",
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},
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],
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"transcript": "NM_001142589.2",
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},
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],
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"gene_symbol": "NFYC",
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"hgvs_c": "c.273+801G>A",
"hgvs_p": null,
"transcript": "ENST00000427410.6",
"protein_id": "ENSP00000408315.2",
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},
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],
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"intron_rank": 1,
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"gene_symbol": "NFYC",
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"hgvs_c": "c.33+801G>A",
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},
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],
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},
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],
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},
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],
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"gene_symbol": "NFYC",
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"hgvs_c": "n.296-4074G>A",
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"transcript": "ENST00000424419.6",
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"feature": null
},
{
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"protein_coding": false,
"strand": true,
"consequences": [
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],
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"exon_count": 6,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NFYC",
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"hgvs_c": "n.615+801G>A",
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},
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}
],
"message": null
}