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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 1-7736507-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=1&pos=7736507&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "1",
"pos": 7736507,
"ref": "A",
"alt": "G",
"effect": "missense_variant",
"transcript": "ENST00000303635.12",
"consequences": [
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "NM_015215.4",
"protein_id": "NP_056030.1",
"transcript_support_level": null,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1673,
"cds_start": 3230,
"cds_end": null,
"cds_length": 5022,
"cdna_start": 3307,
"cdna_end": null,
"cdna_length": 8314,
"mane_select": "ENST00000303635.12",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "ENST00000303635.12",
"protein_id": "ENSP00000306522.6",
"transcript_support_level": 1,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1673,
"cds_start": 3230,
"cds_end": null,
"cds_length": 5022,
"cdna_start": 3307,
"cdna_end": null,
"cdna_length": 8314,
"mane_select": "NM_015215.4",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "ENST00000476864.2",
"protein_id": "ENSP00000452319.2",
"transcript_support_level": 1,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1560,
"cds_start": 3230,
"cds_end": null,
"cds_length": 4683,
"cdna_start": 3243,
"cdna_end": null,
"cdna_length": 6282,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "n.*430A>G",
"hgvs_p": null,
"transcript": "ENST00000495233.6",
"protein_id": "ENSP00000451720.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3678,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "n.*430A>G",
"hgvs_p": null,
"transcript": "ENST00000495233.6",
"protein_id": "ENSP00000451720.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3678,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3140A>G",
"hgvs_p": "p.Tyr1047Cys",
"transcript": "NM_001349608.2",
"protein_id": "NP_001336537.1",
"transcript_support_level": null,
"aa_start": 1047,
"aa_end": null,
"aa_length": 1643,
"cds_start": 3140,
"cds_end": null,
"cds_length": 4932,
"cdna_start": 3237,
"cdna_end": null,
"cdna_length": 8244,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "NM_001349609.2",
"protein_id": "NP_001336538.1",
"transcript_support_level": null,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1567,
"cds_start": 3230,
"cds_end": null,
"cds_length": 4704,
"cdna_start": 3307,
"cdna_end": null,
"cdna_length": 7965,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "NM_001349610.2",
"protein_id": "NP_001336539.1",
"transcript_support_level": null,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1565,
"cds_start": 3230,
"cds_end": null,
"cds_length": 4698,
"cdna_start": 3307,
"cdna_end": null,
"cdna_length": 7990,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3230A>G",
"hgvs_p": "p.Tyr1077Cys",
"transcript": "NM_001410737.1",
"protein_id": "NP_001397666.1",
"transcript_support_level": null,
"aa_start": 1077,
"aa_end": null,
"aa_length": 1560,
"cds_start": 3230,
"cds_end": null,
"cds_length": 4683,
"cdna_start": 3307,
"cdna_end": null,
"cdna_length": 7944,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3140A>G",
"hgvs_p": "p.Tyr1047Cys",
"transcript": "NM_001349612.2",
"protein_id": "NP_001336541.1",
"transcript_support_level": null,
"aa_start": 1047,
"aa_end": null,
"aa_length": 1537,
"cds_start": 3140,
"cds_end": null,
"cds_length": 4614,
"cdna_start": 3237,
"cdna_end": null,
"cdna_length": 7926,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3140A>G",
"hgvs_p": "p.Tyr1047Cys",
"transcript": "ENST00000700415.1",
"protein_id": "ENSP00000514979.1",
"transcript_support_level": null,
"aa_start": 1047,
"aa_end": null,
"aa_length": 1537,
"cds_start": 3140,
"cds_end": null,
"cds_length": 4614,
"cdna_start": 3194,
"cdna_end": null,
"cdna_length": 5986,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3158A>G",
"hgvs_p": "p.Tyr1053Cys",
"transcript": "NM_001410738.1",
"protein_id": "NP_001397667.1",
"transcript_support_level": null,
"aa_start": 1053,
"aa_end": null,
"aa_length": 1536,
"cds_start": 3158,
"cds_end": null,
"cds_length": 4611,
"cdna_start": 3235,
"cdna_end": null,
"cdna_length": 7872,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.3158A>G",
"hgvs_p": "p.Tyr1053Cys",
"transcript": "ENST00000700417.1",
"protein_id": "ENSP00000514981.1",
"transcript_support_level": null,
"aa_start": 1053,
"aa_end": null,
"aa_length": 1536,
"cds_start": 3158,
"cds_end": null,
"cds_length": 4611,
"cdna_start": 3158,
"cdna_end": null,
"cdna_length": 5929,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.1493A>G",
"hgvs_p": "p.Tyr498Cys",
"transcript": "ENST00000700419.1",
"protein_id": "ENSP00000514983.1",
"transcript_support_level": null,
"aa_start": 498,
"aa_end": null,
"aa_length": 955,
"cds_start": 1493,
"cds_end": null,
"cds_length": 2868,
"cdna_start": 1493,
"cdna_end": null,
"cdna_length": 4207,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.893A>G",
"hgvs_p": "p.Tyr298Cys",
"transcript": "ENST00000700445.1",
"protein_id": "ENSP00000514993.1",
"transcript_support_level": null,
"aa_start": 298,
"aa_end": null,
"aa_length": 788,
"cds_start": 893,
"cds_end": null,
"cds_length": 2367,
"cdna_start": 894,
"cdna_end": null,
"cdna_length": 3707,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.359A>G",
"hgvs_p": "p.Tyr120Cys",
"transcript": "NM_001349613.1",
"protein_id": "NP_001336542.1",
"transcript_support_level": null,
"aa_start": 120,
"aa_end": null,
"aa_length": 716,
"cds_start": 359,
"cds_end": null,
"cds_length": 2151,
"cdna_start": 444,
"cdna_end": null,
"cdna_length": 5420,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "NM_001349614.1",
"protein_id": "NP_001336543.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 704,
"cds_start": 302,
"cds_end": null,
"cds_length": 2115,
"cdna_start": 704,
"cdna_end": null,
"cdna_length": 5701,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "NM_001349615.2",
"protein_id": "NP_001336544.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 704,
"cds_start": 302,
"cds_end": null,
"cds_length": 2115,
"cdna_start": 475,
"cdna_end": null,
"cdna_length": 5472,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "NM_001349616.2",
"protein_id": "NP_001336545.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 704,
"cds_start": 302,
"cds_end": null,
"cds_length": 2115,
"cdna_start": 475,
"cdna_end": null,
"cdna_length": 5503,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "NM_001349617.1",
"protein_id": "NP_001336546.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 697,
"cds_start": 302,
"cds_end": null,
"cds_length": 2094,
"cdna_start": 669,
"cdna_end": null,
"cdna_length": 5676,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "NM_001349618.2",
"protein_id": "NP_001336547.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 697,
"cds_start": 302,
"cds_end": null,
"cds_length": 2094,
"cdna_start": 475,
"cdna_end": null,
"cdna_length": 5482,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
"gene_hgnc_id": 18806,
"hgvs_c": "c.302A>G",
"hgvs_p": "p.Tyr101Cys",
"transcript": "ENST00000700421.1",
"protein_id": "ENSP00000514995.1",
"transcript_support_level": null,
"aa_start": 101,
"aa_end": null,
"aa_length": 697,
"cds_start": 302,
"cds_end": null,
"cds_length": 2094,
"cdna_start": 781,
"cdna_end": null,
"cdna_length": 3886,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CAMTA1",
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