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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 1-91502825-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=1&pos=91502825&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "1",
"pos": 91502825,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_003503.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "NM_003503.4",
"protein_id": "NP_003494.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3215,
"mane_select": "ENST00000234626.11",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_003503.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000234626.11",
"protein_id": "ENSP00000234626.6",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3215,
"mane_select": "NM_003503.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000234626.11"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000428239.5",
"protein_id": "ENSP00000393139.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3313,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000428239.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "NM_001134419.2",
"protein_id": "NP_001127891.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3181,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001134419.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "NM_001134420.2",
"protein_id": "NP_001127892.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3309,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001134420.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000897932.1",
"protein_id": "ENSP00000567991.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5022,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897932.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000897933.1",
"protein_id": "ENSP00000567992.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3191,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897933.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000897934.1",
"protein_id": "ENSP00000567993.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3927,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897934.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000897936.1",
"protein_id": "ENSP00000567995.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
"cds_end": null,
"cds_length": 1725,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3157,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897936.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000913030.1",
"protein_id": "ENSP00000583089.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 574,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": 3261,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000913030.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000913034.1",
"protein_id": "ENSP00000583093.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000913034.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 2,
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"gene_symbol": "CDC7",
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"hgvs_c": "c.115+994T>C",
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"transcript": "ENST00000913037.1",
"protein_id": "ENSP00000583096.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 574,
"cds_start": null,
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"feature": "ENST00000913037.1"
},
{
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 2,
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"gene_symbol": "CDC7",
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"hgvs_c": "c.115+994T>C",
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"transcript": "ENST00000913038.1",
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"cdna_start": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 2,
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"gene_symbol": "CDC7",
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"transcript": "ENST00000913029.1",
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},
{
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"strand": true,
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"intron_variant"
],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000913031.1",
"protein_id": "ENSP00000583090.1",
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"cds_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000913031.1"
},
{
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"strand": true,
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],
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"intron_rank": 2,
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"gene_symbol": "CDC7",
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"hgvs_c": "c.115+994T>C",
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"transcript": "ENST00000897935.1",
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},
{
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],
"exon_rank": null,
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"intron_rank": 2,
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"gene_symbol": "CDC7",
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"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000897937.1",
"protein_id": "ENSP00000567996.1",
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"biotype": "protein_coding",
"feature": "ENST00000897937.1"
},
{
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"canonical": false,
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000913032.1",
"protein_id": "ENSP00000583091.1",
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},
{
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"strand": true,
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],
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"intron_rank": 1,
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"hgvs_c": "c.115+994T>C",
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"transcript": "ENST00000913035.1",
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},
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"consequences": [
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],
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"intron_rank": 2,
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"transcript": "ENST00000913036.1",
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},
{
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"strand": true,
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],
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"gene_symbol": "CDC7",
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"hgvs_c": "c.115+994T>C",
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"transcript": "ENST00000913033.1",
"protein_id": "ENSP00000583092.1",
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"cds_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000913033.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CDC7",
"gene_hgnc_id": 1745,
"hgvs_c": "c.115+994T>C",
"hgvs_p": null,
"transcript": "ENST00000426137.1",
"protein_id": "ENSP00000398077.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 156,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000426137.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
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