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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 10-11011180-A-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=10&pos=11011180&ref=A&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "10",
"pos": 11011180,
"ref": "A",
"alt": "C",
"effect": "non_coding_transcript_exon_variant",
"transcript": "XR_007062052.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "ENST00000416382.6",
"protein_id": "ENSP00000406451.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 508,
"cds_start": -4,
"cds_end": null,
"cds_length": 1527,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6894,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CELF2-AS4",
"gene_hgnc_id": 58359,
"hgvs_c": "n.77T>G",
"hgvs_p": null,
"transcript": "XR_007062052.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1254,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.146+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326325.2",
"protein_id": "NP_001313254.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 539,
"cds_start": -4,
"cds_end": null,
"cds_length": 1620,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7933,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "NM_001326336.2",
"protein_id": "NP_001313265.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 532,
"cds_start": -4,
"cds_end": null,
"cds_length": 1599,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 9297,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.89+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326327.2",
"protein_id": "NP_001313256.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 526,
"cds_start": -4,
"cds_end": null,
"cds_length": 1581,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7885,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.89+91181A>C",
"hgvs_p": null,
"transcript": "ENST00000637215.1",
"protein_id": "ENSP00000490185.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 526,
"cds_start": -4,
"cds_end": null,
"cds_length": 1581,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2724,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.89+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326326.2",
"protein_id": "NP_001313255.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 520,
"cds_start": -4,
"cds_end": null,
"cds_length": 1563,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7867,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.89+91181A>C",
"hgvs_p": null,
"transcript": "ENST00000636488.1",
"protein_id": "ENSP00000489955.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 520,
"cds_start": -4,
"cds_end": null,
"cds_length": 1563,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3908,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "NM_001326331.2",
"protein_id": "NP_001313260.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 514,
"cds_start": -4,
"cds_end": null,
"cds_length": 1545,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7885,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "NM_001394502.1",
"protein_id": "NP_001381431.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 514,
"cds_start": -4,
"cds_end": null,
"cds_length": 1545,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 9243,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "ENST00000631816.1",
"protein_id": "ENSP00000488268.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 514,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
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"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "NM_001326335.2",
"protein_id": "NP_001313264.1",
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"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "NM_001025077.3",
"protein_id": "NP_001020248.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.-20+70726A>C",
"hgvs_p": null,
"transcript": "NM_001326319.2",
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},
{
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"strand": true,
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "CELF2",
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"hgvs_c": "c.53+5740A>C",
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"transcript": "NM_001326332.2",
"protein_id": "NP_001313261.1",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 14,
"intron_rank": 1,
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"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.53+5740A>C",
"hgvs_p": null,
"transcript": "ENST00000631460.1",
"protein_id": "ENSP00000488582.1",
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},
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],
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"intron_rank": 4,
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"gene_symbol": "CELF2",
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"hgvs_c": "c.-20+91181A>C",
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"transcript": "NM_001326323.2",
"protein_id": "NP_001313252.1",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 16,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.-20+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326321.2",
"protein_id": "NP_001313250.1",
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"mane_select": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 15,
"intron_rank": 3,
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"gene_symbol": "CELF2",
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"hgvs_c": "c.-20+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326318.2",
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],
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"gene_symbol": "CELF2",
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"hgvs_c": "c.-20+91181A>C",
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},
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],
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"intron_rank": 2,
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"gene_symbol": "CELF2",
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},
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"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.-20+91181A>C",
"hgvs_p": null,
"transcript": "NM_001326328.2",
"protein_id": "NP_001313257.1",
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"aa_start": null,
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"mane_select": null,
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CELF2",
"gene_hgnc_id": 2550,
"hgvs_c": "c.-20+6182A>C",
"hgvs_p": null,
"transcript": "NM_001326330.2",
"protein_id": "NP_001313259.1",
"transcript_support_level": null,
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{
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{
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{
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],
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}
],
"message": null
}