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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 10-33236908-T-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=10&pos=33236908&ref=T&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "10",
"pos": 33236908,
"ref": "T",
"alt": "A",
"effect": "intron_variant",
"transcript": "NM_003873.7",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "NM_003873.7",
"protein_id": "NP_003864.5",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 923,
"cds_start": null,
"cds_end": null,
"cds_length": 2772,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000374867.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_003873.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374867.7",
"protein_id": "ENSP00000364001.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 923,
"cds_start": null,
"cds_end": null,
"cds_length": 2772,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_003873.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374867.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000395995.5",
"protein_id": "ENSP00000379317.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 906,
"cds_start": null,
"cds_end": null,
"cds_length": 2721,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000395995.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.439-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374875.5",
"protein_id": "ENSP00000364009.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
"cds_end": null,
"cds_length": 2208,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374875.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374823.9",
"protein_id": "ENSP00000363956.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 704,
"cds_start": null,
"cds_end": null,
"cds_length": 2115,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374823.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374822.8",
"protein_id": "ENSP00000363955.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 644,
"cds_start": null,
"cds_end": null,
"cds_length": 1935,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374822.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374816.7",
"protein_id": "ENSP00000363949.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 641,
"cds_start": null,
"cds_end": null,
"cds_length": 1926,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374816.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000374821.9",
"protein_id": "ENSP00000363954.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 609,
"cds_start": null,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000374821.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000432372.6",
"protein_id": "ENSP00000408911.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 597,
"cds_start": null,
"cds_end": null,
"cds_length": 1794,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000432372.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000897564.1",
"protein_id": "ENSP00000567623.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 924,
"cds_start": null,
"cds_end": null,
"cds_length": 2775,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897564.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000265371.8",
"protein_id": "ENSP00000265371.3",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 923,
"cds_start": null,
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"cds_length": 2772,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000265371.8"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949864.1",
"protein_id": "ENSP00000619923.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 922,
"cds_start": null,
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"cds_length": 2769,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000949864.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949868.1",
"protein_id": "ENSP00000619927.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 920,
"cds_start": null,
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"cds_length": 2763,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000949868.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 6,
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"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "NM_001244972.2",
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"cdna_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001244972.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000897565.1",
"protein_id": "ENSP00000567624.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 917,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897565.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 6,
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"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "NM_001244973.2",
"protein_id": "NP_001231902.2",
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001244973.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949862.1",
"protein_id": "ENSP00000619921.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000949862.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949863.1",
"protein_id": "ENSP00000619922.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000949863.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949872.1",
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},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
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"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "NM_001330068.2",
"protein_id": "NP_001316997.2",
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"feature": "NM_001330068.2"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000949861.1",
"protein_id": "ENSP00000619920.1",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000949861.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "NRP1",
"gene_hgnc_id": 8004,
"hgvs_c": "c.982-10619A>T",
"hgvs_p": null,
"transcript": "ENST00000897563.1",
"protein_id": "ENSP00000567622.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 888,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897563.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
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