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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 10-38095711-T-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=10&pos=38095711&ref=T&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "10",
"pos": 38095711,
"ref": "T",
"alt": "A",
"effect": "intron_variant",
"transcript": "ENST00000685332.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324250.3",
"protein_id": "NP_001311179.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8119,
"mane_select": "ENST00000685332.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "ENST00000685332.1",
"protein_id": "ENSP00000508865.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8119,
"mane_select": "NM_001324250.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "ENST00000351773.7",
"protein_id": "ENSP00000329141.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7027,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "PLD5P1",
"gene_hgnc_id": 55072,
"hgvs_c": "n.-105-33T>A",
"hgvs_p": null,
"transcript": "ENST00000640275.1",
"protein_id": "ENSP00000491560.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3955,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001007094.4",
"protein_id": "NP_001007095.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8303,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001178101.3",
"protein_id": "NP_001171572.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7825,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324245.3",
"protein_id": "NP_001311174.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 7754,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324246.3",
"protein_id": "NP_001311175.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8299,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324247.3",
"protein_id": "NP_001311176.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 561,
"cds_start": -4,
"cds_end": null,
"cds_length": 1686,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 8044,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 2,
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"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324248.3",
"protein_id": "NP_001311177.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"feature": null
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
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"gene_symbol": "ZNF37A",
"gene_hgnc_id": 13102,
"hgvs_c": "c.-105-33T>A",
"hgvs_p": null,
"transcript": "NM_001324249.3",
"protein_id": "NP_001311178.1",
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},
{
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],
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"gene_symbol": "ZNF37A",
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"transcript": "NM_001324251.3",
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},
{
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],
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"gene_symbol": "ZNF37A",
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"hgvs_c": "c.-105-33T>A",
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"transcript": "NM_003421.4",
"protein_id": "NP_003412.1",
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},
{
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],
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"gene_symbol": "ZNF37A",
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"transcript": "ENST00000361085.9",
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],
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},
{
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],
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"gene_symbol": "ZNF37A",
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"gene_symbol": "ZNF37A",
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},
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],
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"gene_symbol": "ZNF37A",
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"hgvs_c": "c.-105-33T>A",
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"transcript": "NM_001324256.2",
"protein_id": "NP_001311185.1",
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"intron_rank": 3,
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"gene_symbol": "ZNF37A",
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],
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],
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"gene_symbol": "ZNF37A",
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"hgvs_c": "c.-105-33T>A",
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},
{
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"strand": true,
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],
"exon_rank": null,
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"intron_rank": 2,
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"gene_symbol": "ZNF37A",
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"hgvs_c": "c.-105-33T>A",
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"transcript": "NM_001324260.3",
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},
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{
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},
{
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}
],
"message": null
}