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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 10-5739665-T-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=10&pos=5739665&ref=T&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "10",
"pos": 5739665,
"ref": "T",
"alt": "G",
"effect": "missense_variant",
"transcript": "NM_001387328.1",
"consequences": [
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "NM_001321783.2",
"protein_id": "NP_001308712.2",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000695737.1",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001321783.2"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000695737.1",
"protein_id": "ENSP00000512130.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001321783.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000695737.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000328090.9",
"protein_id": "ENSP00000328426.5",
"transcript_support_level": 1,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000328090.9"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 17,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.2278T>G",
"hgvs_p": "p.Cys760Gly",
"transcript": "ENST00000699051.1",
"protein_id": "ENSP00000514102.1",
"transcript_support_level": null,
"aa_start": 760,
"aa_end": null,
"aa_length": 2691,
"cds_start": 2278,
"cds_end": null,
"cds_length": 8076,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000699051.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 16,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.2200T>G",
"hgvs_p": "p.Cys734Gly",
"transcript": "ENST00000699050.1",
"protein_id": "ENSP00000514101.1",
"transcript_support_level": null,
"aa_start": 734,
"aa_end": null,
"aa_length": 2665,
"cds_start": 2200,
"cds_end": null,
"cds_length": 7998,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000699050.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 16,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.2140T>G",
"hgvs_p": "p.Cys714Gly",
"transcript": "NM_001387328.1",
"protein_id": "NP_001374257.1",
"transcript_support_level": null,
"aa_start": 714,
"aa_end": null,
"aa_length": 2645,
"cds_start": 2140,
"cds_end": null,
"cds_length": 7938,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001387328.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 16,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.2140T>G",
"hgvs_p": "p.Cys714Gly",
"transcript": "ENST00000645567.1",
"protein_id": "ENSP00000496466.1",
"transcript_support_level": null,
"aa_start": 714,
"aa_end": null,
"aa_length": 2645,
"cds_start": 2140,
"cds_end": null,
"cds_length": 7938,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000645567.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1747T>G",
"hgvs_p": "p.Cys583Gly",
"transcript": "ENST00000695832.1",
"protein_id": "ENSP00000512205.1",
"transcript_support_level": null,
"aa_start": 583,
"aa_end": null,
"aa_length": 2514,
"cds_start": 1747,
"cds_end": null,
"cds_length": 7545,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000695832.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "NM_001321784.2",
"protein_id": "NP_001308713.2",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001321784.2"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "NM_017782.5",
"protein_id": "NP_060252.5",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_017782.5"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000695834.1",
"protein_id": "ENSP00000512207.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000695834.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000873841.1",
"protein_id": "ENSP00000543900.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000873841.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914613.1",
"protein_id": "ENSP00000584672.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914613.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 15,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914614.1",
"protein_id": "ENSP00000584673.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914614.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 11,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914615.1",
"protein_id": "ENSP00000584674.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914615.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 11,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914616.1",
"protein_id": "ENSP00000584675.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914616.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914617.1",
"protein_id": "ENSP00000584676.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914617.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 15,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914618.1",
"protein_id": "ENSP00000584677.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914618.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914619.1",
"protein_id": "ENSP00000584678.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914619.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1495T>G",
"hgvs_p": "p.Cys499Gly",
"transcript": "ENST00000914620.1",
"protein_id": "ENSP00000584679.1",
"transcript_support_level": null,
"aa_start": 499,
"aa_end": null,
"aa_length": 2430,
"cds_start": 1495,
"cds_end": null,
"cds_length": 7293,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914620.1"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1252T>G",
"hgvs_p": "p.Cys418Gly",
"transcript": "NM_001321785.2",
"protein_id": "NP_001308714.2",
"transcript_support_level": null,
"aa_start": 418,
"aa_end": null,
"aa_length": 2349,
"cds_start": 1252,
"cds_end": null,
"cds_length": 7050,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001321785.2"
},
{
"aa_ref": "C",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TASOR2",
"gene_hgnc_id": 23484,
"hgvs_c": "c.1252T>G",
"hgvs_p": "p.Cys418Gly",
"transcript": "ENST00000695833.1",
"protein_id": "ENSP00000512206.1",
"transcript_support_level": null,
"aa_start": 418,
"aa_end": null,
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{
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],
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}
],
"message": null
}