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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 10-96880089-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=10&pos=96880089&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "10",
"pos": 96880089,
"ref": "G",
"alt": "A",
"effect": "intron_variant",
"transcript": "NM_001346516.2",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "NM_001346516.2",
"protein_id": "NP_001333445.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000421806.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001346516.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000421806.4",
"protein_id": "ENSP00000490116.2",
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001346516.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000421806.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000371097.8",
"protein_id": "ENSP00000360138.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 433,
"cds_start": null,
"cds_end": null,
"cds_length": 1302,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000371097.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000371103.8",
"protein_id": "ENSP00000360144.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 433,
"cds_start": null,
"cds_end": null,
"cds_length": 1302,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000371103.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000540664.6",
"protein_id": "ENSP00000443431.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000540664.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000874571.1",
"protein_id": "ENSP00000544630.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000874571.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000874572.1",
"protein_id": "ENSP00000544631.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000874572.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000874573.1",
"protein_id": "ENSP00000544632.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000874573.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000931941.1",
"protein_id": "ENSP00000602000.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000931941.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-330+21673G>A",
"hgvs_p": null,
"transcript": "ENST00000931942.1",
"protein_id": "ENSP00000602001.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
"cds_end": null,
"cds_length": 4674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000931942.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000931943.1",
"protein_id": "ENSP00000602002.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000931943.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000931944.1",
"protein_id": "ENSP00000602003.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1557,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000931944.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.74-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000675117.1",
"protein_id": "ENSP00000502330.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 660,
"cds_start": null,
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"cds_length": 1983,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000675117.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 8,
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"intron_rank_end": null,
"gene_symbol": "LCOR",
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"hgvs_c": "c.152-27176G>A",
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"transcript": "ENST00000674725.1",
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"cdna_start": null,
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"feature": "ENST00000674725.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.98-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000676123.1",
"protein_id": "ENSP00000501887.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 575,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000676123.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 8,
"intron_rank": 1,
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"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.233-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000676381.1",
"protein_id": "ENSP00000501937.1",
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"biotype": "protein_coding",
"feature": "ENST00000676381.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.47-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000676187.1",
"protein_id": "ENSP00000502316.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000676187.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000675687.1",
"protein_id": "ENSP00000502138.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000675687.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "NM_001170765.2",
"protein_id": "NP_001164236.1",
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"feature": "NM_001170765.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "NM_032440.4",
"protein_id": "NP_115816.2",
"transcript_support_level": null,
"aa_start": null,
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"biotype": "protein_coding",
"feature": "NM_032440.4"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
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"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-329-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000356016.7",
"protein_id": "ENSP00000348298.2",
"transcript_support_level": 2,
"aa_start": null,
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"aa_length": 433,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000356016.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "LCOR",
"gene_hgnc_id": 29503,
"hgvs_c": "c.-340-27176G>A",
"hgvs_p": null,
"transcript": "ENST00000675471.1",
"protein_id": "ENSP00000502633.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 433,
"cds_start": null,
"cds_end": null,
"cds_length": 1302,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000675471.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 2,
"intron_rank_end": null,
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}