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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 11-44845386-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=11&pos=44845386&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "11",
"pos": 44845386,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_130783.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-152-14942T>C",
"hgvs_p": null,
"transcript": "NM_130783.5",
"protein_id": "NP_570139.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4557,
"mane_select": "ENST00000520358.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_130783.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-152-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000520358.7",
"protein_id": "ENSP00000429993.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4557,
"mane_select": "NM_130783.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000520358.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-152-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000340160.7",
"protein_id": "ENSP00000339820.3",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4229,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000340160.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-229-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860337.1",
"protein_id": "ENSP00000530396.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4480,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860337.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-229-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860338.1",
"protein_id": "ENSP00000530397.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4612,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860338.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-238-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860339.1",
"protein_id": "ENSP00000530398.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3361,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860339.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-120-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860340.1",
"protein_id": "ENSP00000530399.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3164,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860340.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-285-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860341.1",
"protein_id": "ENSP00000530400.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
"cds_length": 747,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3617,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860341.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-229-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860342.1",
"protein_id": "ENSP00000530401.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 248,
"cds_start": null,
"cds_end": null,
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"cdna_start": null,
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"cdna_length": 3508,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860342.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-161-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860344.1",
"protein_id": "ENSP00000530403.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": 2110,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000860344.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 2,
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"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-229-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000860345.1",
"protein_id": "ENSP00000530404.1",
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"cds_start": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-268-2475T>C",
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"transcript": "ENST00000860346.1",
"protein_id": "ENSP00000530405.1",
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"biotype": "protein_coding",
"feature": "ENST00000860346.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 2,
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-389-13083T>C",
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"protein_id": "ENSP00000530406.1",
"transcript_support_level": null,
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},
{
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],
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},
{
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"protein_coding": true,
"strand": true,
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"intron_variant"
],
"exon_rank": null,
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"intron_rank": 2,
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"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-312-13083T>C",
"hgvs_p": null,
"transcript": "ENST00000924264.1",
"protein_id": "ENSP00000594323.1",
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},
{
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],
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-152-14942T>C",
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},
{
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 2,
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-424-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000955998.1",
"protein_id": "ENSP00000626057.1",
"transcript_support_level": null,
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},
{
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 9,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-152-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000955999.1",
"protein_id": "ENSP00000626058.1",
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},
{
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],
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"gene_symbol": "TSPAN18",
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},
{
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"strand": true,
"consequences": [
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],
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-199-14942T>C",
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"transcript": "ENST00000520999.6",
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},
{
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],
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"gene_symbol": "TSPAN18",
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"hgvs_c": "c.-152-14942T>C",
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"transcript": "ENST00000533786.5",
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"transcript_support_level": 4,
"aa_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000533786.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "TSPAN18",
"gene_hgnc_id": 20660,
"hgvs_c": "c.-152-14942T>C",
"hgvs_p": null,
"transcript": "ENST00000533080.5",
"protein_id": "ENSP00000433362.1",
"transcript_support_level": 3,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000533080.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
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}