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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 11-61556451-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=11&pos=61556451&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "11",
"pos": 61556451,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_001365809.2",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "NM_001365809.2",
"protein_id": "NP_001352738.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 686,
"cds_start": null,
"cds_end": null,
"cds_length": 2061,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000539008.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001365809.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000539008.6",
"protein_id": "ENSP00000439694.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 686,
"cds_start": null,
"cds_end": null,
"cds_length": 2061,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001365809.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000539008.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000540677.5",
"protein_id": "ENSP00000444201.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 478,
"cds_start": null,
"cds_end": null,
"cds_length": 1437,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000540677.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000263846.8",
"protein_id": "ENSP00000263846.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 403,
"cds_start": null,
"cds_end": null,
"cds_length": 1212,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000263846.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000542670.5",
"protein_id": "ENSP00000444019.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 611,
"cds_start": null,
"cds_end": null,
"cds_length": 1836,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000542670.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "NM_001411007.1",
"protein_id": "NP_001397936.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 522,
"cds_start": null,
"cds_end": null,
"cds_length": 1569,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001411007.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000535826.5",
"protein_id": "ENSP00000437720.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 522,
"cds_start": null,
"cds_end": null,
"cds_length": 1569,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000535826.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000968863.1",
"protein_id": "ENSP00000638922.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 491,
"cds_start": null,
"cds_end": null,
"cds_length": 1476,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000968863.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "NM_001252065.2",
"protein_id": "NP_001238994.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 478,
"cds_start": null,
"cds_end": null,
"cds_length": 1437,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001252065.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "NM_001300773.2",
"protein_id": "NP_001287702.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 447,
"cds_start": null,
"cds_end": null,
"cds_length": 1344,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001300773.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000542836.5",
"protein_id": "ENSP00000444568.1",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000542836.5"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 10,
"intron_rank": 1,
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"gene_symbol": "SYT7",
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"hgvs_c": "c.32-244G>A",
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"transcript": "ENST00000933166.1",
"protein_id": "ENSP00000603225.1",
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"aa_start": null,
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"cds_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000933166.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 9,
"intron_rank": 1,
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"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "NM_004200.4",
"protein_id": "NP_004191.2",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"feature": "NM_004200.4"
},
{
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"strand": false,
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "SYT7",
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"hgvs_c": "c.32-244G>A",
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"transcript": "NM_001370211.1",
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},
{
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"protein_coding": true,
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"intron_variant"
],
"exon_rank": null,
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"exon_count": 9,
"intron_rank": 1,
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"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "ENST00000933167.1",
"protein_id": "ENSP00000603226.1",
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"cds_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000933167.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
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"transcript": "ENST00000545053.1",
"protein_id": "ENSP00000443576.1",
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"biotype": "protein_coding",
"feature": "ENST00000545053.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 1,
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"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.50-244G>A",
"hgvs_p": null,
"transcript": "XM_011545335.3",
"protein_id": "XP_011543637.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.50-244G>A",
"hgvs_p": null,
"transcript": "XM_011545336.3",
"protein_id": "XP_011543638.1",
"transcript_support_level": null,
"aa_start": null,
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},
{
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"strand": false,
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "SYT7",
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"hgvs_c": "c.50-244G>A",
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"transcript": "XM_011545337.3",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "SYT7",
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"hgvs_c": "c.32-244G>A",
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"transcript": "XM_005274384.3",
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},
{
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],
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"intron_rank": 1,
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"gene_symbol": "SYT7",
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"biotype": "protein_coding",
"feature": "XM_011545338.3"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SYT7",
"gene_hgnc_id": 11514,
"hgvs_c": "c.32-244G>A",
"hgvs_p": null,
"transcript": "XM_005274385.5",
"protein_id": "XP_005274442.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 611,
"cds_start": null,
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"cdna_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_005274385.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
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}