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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 11-836088-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=11&pos=836088&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "11",
"pos": 836088,
"ref": "A",
"alt": "G",
"effect": "missense_variant",
"transcript": "NM_004357.5",
"consequences": [
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "NM_004357.5",
"protein_id": "NP_004348.2",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000397420.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_004357.5"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000397420.9",
"protein_id": "ENSP00000380565.3",
"transcript_support_level": 1,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_004357.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000397420.9"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000322008.9",
"protein_id": "ENSP00000324101.4",
"transcript_support_level": 1,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000322008.9"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000397421.5",
"protein_id": "ENSP00000380566.1",
"transcript_support_level": 1,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000397421.5"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890775.1",
"protein_id": "ENSP00000560834.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 286,
"cds_start": 19,
"cds_end": null,
"cds_length": 861,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890775.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890776.1",
"protein_id": "ENSP00000560835.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 263,
"cds_start": 19,
"cds_end": null,
"cds_length": 792,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890776.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890784.1",
"protein_id": "ENSP00000560843.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 263,
"cds_start": 19,
"cds_end": null,
"cds_length": 792,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890784.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890788.1",
"protein_id": "ENSP00000560847.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 263,
"cds_start": 19,
"cds_end": null,
"cds_length": 792,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890788.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000919380.1",
"protein_id": "ENSP00000589439.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 260,
"cds_start": 19,
"cds_end": null,
"cds_length": 783,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000919380.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000946305.1",
"protein_id": "ENSP00000616364.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 260,
"cds_start": 19,
"cds_end": null,
"cds_length": 783,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000946305.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "NM_001039490.2",
"protein_id": "NP_001034579.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001039490.2"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "NM_139029.2",
"protein_id": "NP_620598.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_139029.2"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "NM_139030.4",
"protein_id": "NP_620599.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_139030.4"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890766.1",
"protein_id": "ENSP00000560825.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890766.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890768.1",
"protein_id": "ENSP00000560827.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890768.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890769.1",
"protein_id": "ENSP00000560828.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890769.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890774.1",
"protein_id": "ENSP00000560833.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890774.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890777.1",
"protein_id": "ENSP00000560836.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890777.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890778.1",
"protein_id": "ENSP00000560837.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890778.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890779.1",
"protein_id": "ENSP00000560838.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890779.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890782.1",
"protein_id": "ENSP00000560841.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890782.1"
},
{
"aa_ref": "K",
"aa_alt": "E",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CD151",
"gene_hgnc_id": 1630,
"hgvs_c": "c.19A>G",
"hgvs_p": "p.Lys7Glu",
"transcript": "ENST00000890783.1",
"protein_id": "ENSP00000560842.1",
"transcript_support_level": null,
"aa_start": 7,
"aa_end": null,
"aa_length": 253,
"cds_start": 19,
"cds_end": null,
"cds_length": 762,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000890783.1"
},
{
"aa_ref": "K",
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