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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 12-6374399-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=12&pos=6374399&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "12",
"pos": 6374399,
"ref": "C",
"alt": "T",
"effect": "missense_variant",
"transcript": "NM_001159576.2",
"consequences": [
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "NM_001038.6",
"protein_id": "NP_001029.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000228916.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001038.6"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000228916.7",
"protein_id": "ENSP00000228916.2",
"transcript_support_level": 1,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001038.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000228916.7"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.562G>A",
"hgvs_p": "p.Ala188Thr",
"transcript": "ENST00000360168.7",
"protein_id": "ENSP00000353292.3",
"transcript_support_level": 1,
"aa_start": 188,
"aa_end": null,
"aa_length": 728,
"cds_start": 562,
"cds_end": null,
"cds_length": 2187,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000360168.7"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.562G>A",
"hgvs_p": "p.Ala188Thr",
"transcript": "NM_001159576.2",
"protein_id": "NP_001153048.1",
"transcript_support_level": null,
"aa_start": 188,
"aa_end": null,
"aa_length": 728,
"cds_start": 562,
"cds_end": null,
"cds_length": 2187,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001159576.2"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.454G>A",
"hgvs_p": "p.Ala152Thr",
"transcript": "NM_001159575.2",
"protein_id": "NP_001153047.1",
"transcript_support_level": null,
"aa_start": 152,
"aa_end": null,
"aa_length": 692,
"cds_start": 454,
"cds_end": null,
"cds_length": 2079,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001159575.2"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.454G>A",
"hgvs_p": "p.Ala152Thr",
"transcript": "ENST00000543768.1",
"protein_id": "ENSP00000438739.1",
"transcript_support_level": 2,
"aa_start": 152,
"aa_end": null,
"aa_length": 692,
"cds_start": 454,
"cds_end": null,
"cds_length": 2079,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000543768.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868221.1",
"protein_id": "ENSP00000538280.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868221.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868222.1",
"protein_id": "ENSP00000538281.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868222.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868223.1",
"protein_id": "ENSP00000538282.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868223.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868224.1",
"protein_id": "ENSP00000538283.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868224.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868225.1",
"protein_id": "ENSP00000538284.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868225.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868226.1",
"protein_id": "ENSP00000538285.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868226.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868227.1",
"protein_id": "ENSP00000538286.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868227.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868228.1",
"protein_id": "ENSP00000538287.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868228.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868229.1",
"protein_id": "ENSP00000538288.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868229.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868230.1",
"protein_id": "ENSP00000538289.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868230.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868231.1",
"protein_id": "ENSP00000538290.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868231.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000868232.1",
"protein_id": "ENSP00000538291.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868232.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000930631.1",
"protein_id": "ENSP00000600690.1",
"transcript_support_level": null,
"aa_start": 129,
"aa_end": null,
"aa_length": 669,
"cds_start": 385,
"cds_end": null,
"cds_length": 2010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930631.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.385G>A",
"hgvs_p": "p.Ala129Thr",
"transcript": "ENST00000396966.6",
"protein_id": "ENSP00000380166.2",
"transcript_support_level": 3,
"aa_start": 129,
"aa_end": null,
"aa_length": 511,
"cds_start": 385,
"cds_end": null,
"cds_length": 1536,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000396966.6"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "c.448G>A",
"hgvs_p": "p.Ala150Thr",
"transcript": "ENST00000536788.1",
"protein_id": "ENSP00000443434.1",
"transcript_support_level": 4,
"aa_start": 150,
"aa_end": null,
"aa_length": 158,
"cds_start": 448,
"cds_end": null,
"cds_length": 478,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000536788.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"hgvs_c": "n.385G>A",
"hgvs_p": null,
"transcript": "ENST00000338748.9",
"protein_id": "ENSP00000345028.5",
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
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{
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"biotype": "pseudogene",
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{
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"protein_coding": false,
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{
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"feature": "ENST00000544882.1"
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{
"aa_ref": null,
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
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"exon_count": 6,
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"gene_symbol": "SCNN1A",
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{
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"downstream_gene_variant"
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"exon_count": 3,
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{
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"downstream_gene_variant"
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{
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"downstream_gene_variant"
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"gene_symbol": "SCNN1A",
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"hgvs_c": "n.*67G>A",
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"transcript": "ENST00000542436.1",
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{
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"downstream_gene_variant"
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"exon_count": 4,
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"gene_symbol": "SCNN1A",
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"hgvs_c": "n.*227G>A",
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"transcript": "ENST00000545605.1",
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"cdna_length": null,
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"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000545605.1"
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],
"gene_symbol": "SCNN1A",
"gene_hgnc_id": 10599,
"dbsnp": "rs141756749",
"frequency_reference_population": 0.000041510382,
"hom_count_reference_population": 1,
"allele_count_reference_population": 67,
"gnomad_exomes_af": 0.0000424115,
"gnomad_genomes_af": 0.0000328541,
"gnomad_exomes_ac": 62,
"gnomad_genomes_ac": 5,
"gnomad_exomes_homalt": 1,
"gnomad_genomes_homalt": 0,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": 0.8450931310653687,
"computational_prediction_selected": "Pathogenic",
"computational_source_selected": "MetaRNN",
"splice_score_selected": 0.009999999776482582,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": 0.599,
"revel_prediction": "Uncertain_significance",
"alphamissense_score": 0.4033,
"alphamissense_prediction": null,
"bayesdelnoaf_score": 0.07,
"bayesdelnoaf_prediction": "Uncertain_significance",
"phylop100way_score": 5.841,
"phylop100way_prediction": "Uncertain_significance",
"spliceai_max_score": 0.01,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": 2,
"acmg_classification": "Uncertain_significance",
"acmg_criteria": "PP3_Moderate",
"acmg_by_gene": [
{
"score": 2,
"benign_score": 0,
"pathogenic_score": 2,
"criteria": [
"PP3_Moderate"
],
"verdict": "Uncertain_significance",
"transcript": "NM_001159576.2",
"gene_symbol": "SCNN1A",
"hgnc_id": 10599,
"effects": [
"missense_variant"
],
"inheritance_mode": "AR,Unknown,AD",
"hgvs_c": "c.562G>A",
"hgvs_p": "p.Ala188Thr"
}
],
"clinvar_disease": " autosomal recessive, type IB1,Bronchiectasis with or without elevated sweat chloride 2,Liddle syndrome 3,Pseudohypoaldosteronism,not provided",
"clinvar_classification": "Uncertain significance",
"clinvar_review_status": "criteria provided, multiple submitters, no conflicts",
"clinvar_submissions_summary": "US:4",
"phenotype_combined": "Pseudohypoaldosteronism, type IB1, autosomal recessive|Bronchiectasis with or without elevated sweat chloride 2|Bronchiectasis with or without elevated sweat chloride 2;Liddle syndrome 3;Pseudohypoaldosteronism, type IB1, autosomal recessive|not provided",
"pathogenicity_classification_combined": "Uncertain significance",
"custom_annotations": null
}
],
"message": null
}