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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 13-32407005-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=13&pos=32407005&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "13",
"pos": 32407005,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "ENST00000380130.7",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "NM_052818.3",
"protein_id": "NP_438169.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 243,
"cds_start": -4,
"cds_end": null,
"cds_length": 732,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2999,
"mane_select": "ENST00000380130.7",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "ENST00000380130.7",
"protein_id": "ENSP00000369473.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 243,
"cds_start": -4,
"cds_end": null,
"cds_length": 732,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2999,
"mane_select": "NM_052818.3",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "ENST00000380133.6",
"protein_id": "ENSP00000369476.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 243,
"cds_start": -4,
"cds_end": null,
"cds_length": 732,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 903,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "ENST00000380139.8",
"protein_id": "ENSP00000369484.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 173,
"cds_start": -4,
"cds_end": null,
"cds_length": 522,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2994,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "n.871G>A",
"hgvs_p": null,
"transcript": "ENST00000472298.1",
"protein_id": null,
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1423,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.672+245G>A",
"hgvs_p": null,
"transcript": "NM_001353627.2",
"protein_id": "NP_001340556.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 335,
"cds_start": -4,
"cds_end": null,
"cds_length": 1008,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3275,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.672+245G>A",
"hgvs_p": null,
"transcript": "NM_001353628.2",
"protein_id": "NP_001340557.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 265,
"cds_start": -4,
"cds_end": null,
"cds_length": 798,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3267,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.438+245G>A",
"hgvs_p": null,
"transcript": "NM_001353629.2",
"protein_id": "NP_001340558.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 257,
"cds_start": -4,
"cds_end": null,
"cds_length": 774,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3481,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "NM_001286459.2",
"protein_id": "NP_001273388.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 243,
"cds_start": -4,
"cds_end": null,
"cds_length": 732,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1993,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "NM_001353630.2",
"protein_id": "NP_001340559.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 204,
"cds_start": -4,
"cds_end": null,
"cds_length": 615,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3097,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.438+245G>A",
"hgvs_p": null,
"transcript": "NM_001353631.2",
"protein_id": "NP_001340560.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 202,
"cds_start": -4,
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"cds_length": 609,
"cdna_start": null,
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"mane_select": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "NM_001353632.2",
"protein_id": "NP_001340561.1",
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"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.228+245G>A",
"hgvs_p": null,
"transcript": "NM_001353633.2",
"protein_id": "NP_001340562.1",
"transcript_support_level": null,
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"cds_start": -4,
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"cdna_start": null,
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"feature": null
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "NM_001286460.2",
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},
{
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],
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"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
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"hgvs_c": "c.396+245G>A",
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"transcript": "NM_001286461.2",
"protein_id": "NP_001273390.1",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
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"hgvs_c": "c.396+245G>A",
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"transcript": "NM_001079691.2",
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},
{
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],
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"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.396+245G>A",
"hgvs_p": null,
"transcript": "ENST00000613078.4",
"protein_id": "ENSP00000483310.1",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.327+245G>A",
"hgvs_p": null,
"transcript": "ENST00000635608.1",
"protein_id": "ENSP00000489423.1",
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},
{
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"protein_coding": true,
"strand": false,
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],
"exon_rank": null,
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"intron_rank": 3,
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"gene_symbol": "N4BP2L1",
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"hgvs_c": "c.327+245G>A",
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"transcript": "ENST00000495479.5",
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},
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],
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"gene_symbol": "N4BP2L1",
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"transcript": "NM_001353634.2",
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},
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],
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"gene_symbol": "N4BP2L1",
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},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.78+245G>A",
"hgvs_p": null,
"transcript": "ENST00000530622.6",
"protein_id": "ENSP00000435515.2",
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"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 1897,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "N4BP2L1",
"gene_hgnc_id": 25037,
"hgvs_c": "c.307+640G>A",
"hgvs_p": null,
"transcript": "NM_001353636.2",
"protein_id": "NP_001340565.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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