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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 13-42291061-C-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=13&pos=42291061&ref=C&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "13",
"pos": 42291061,
"ref": "C",
"alt": "G",
"effect": "intron_variant",
"transcript": "NM_016248.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "NM_016248.4",
"protein_id": "NP_057332.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000025301.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_016248.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000025301.4",
"protein_id": "ENSP00000025301.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_016248.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000025301.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000938569.1",
"protein_id": "ENSP00000608628.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938569.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000938572.1",
"protein_id": "ENSP00000608631.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938572.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000938570.1",
"protein_id": "ENSP00000608629.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1873,
"cds_start": null,
"cds_end": null,
"cds_length": 5622,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938570.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000938571.1",
"protein_id": "ENSP00000608630.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1873,
"cds_start": null,
"cds_end": null,
"cds_length": 5622,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938571.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-4634C>G",
"hgvs_p": null,
"transcript": "ENST00000938573.1",
"protein_id": "ENSP00000608632.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1862,
"cds_start": null,
"cds_end": null,
"cds_length": 5589,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938573.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "ENST00000938574.1",
"protein_id": "ENSP00000608633.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1856,
"cds_start": null,
"cds_end": null,
"cds_length": 5571,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000938574.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_011534903.3",
"protein_id": "XP_011533205.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011534903.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_011534904.2",
"protein_id": "XP_011533206.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1901,
"cds_start": null,
"cds_end": null,
"cds_length": 5706,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011534904.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_011534905.2",
"protein_id": "XP_011533207.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_011534905.2"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_011534906.3",
"protein_id": "XP_011533208.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1901,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_011534906.3"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_017020381.3",
"protein_id": "XP_016875870.1",
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017020381.3"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 3,
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"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
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"transcript": "XM_005266247.2",
"protein_id": "XP_005266304.1",
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"biotype": "protein_coding",
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},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_047430072.1",
"protein_id": "XP_047286028.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047430072.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
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"transcript": "XM_047430073.1",
"protein_id": "XP_047286029.1",
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"biotype": "protein_coding",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_047430074.1",
"protein_id": "XP_047286030.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
"feature": "XM_047430074.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_047430075.1",
"protein_id": "XP_047286031.1",
"transcript_support_level": null,
"aa_start": null,
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"biotype": "protein_coding",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 3,
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"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_005266248.4",
"protein_id": "XP_005266305.1",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_017020382.2",
"protein_id": "XP_016875871.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
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"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_017020383.2",
"protein_id": "XP_016875872.1",
"transcript_support_level": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017020383.2"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "AKAP11",
"gene_hgnc_id": 369,
"hgvs_c": "c.52-1324C>G",
"hgvs_p": null,
"transcript": "XM_047430076.1",
"protein_id": "XP_047286032.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047430076.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 12,
"intron_rank": 3,
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}