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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 14-102001510-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=14&pos=102001510&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "14",
"pos": 102001510,
"ref": "A",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000360184.10",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 78,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "NM_001376.5",
"protein_id": "NP_001367.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 4646,
"cds_start": -4,
"cds_end": null,
"cds_length": 13941,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 19940,
"mane_select": "ENST00000360184.10",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 78,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000360184.10",
"protein_id": "ENSP00000348965.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 4646,
"cds_start": -4,
"cds_end": null,
"cds_length": 13941,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 19940,
"mane_select": "NM_001376.5",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 77,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000681574.1",
"protein_id": "ENSP00000505523.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 4672,
"cds_start": -4,
"cds_end": null,
"cds_length": 14019,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 14519,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 78,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000679720.1",
"protein_id": "ENSP00000505938.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 4637,
"cds_start": -4,
"cds_end": null,
"cds_length": 13914,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 19903,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 78,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000644881.2",
"protein_id": "ENSP00000495022.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 4604,
"cds_start": -4,
"cds_end": null,
"cds_length": 13815,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 14291,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 77,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000645149.2",
"protein_id": "ENSP00000495944.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 4597,
"cds_start": -4,
"cds_end": null,
"cds_length": 13794,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 14134,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 58,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000680137.1",
"protein_id": "ENSP00000505294.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3668,
"cds_start": -4,
"cds_end": null,
"cds_length": 11007,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 11328,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 57,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000643508.2",
"protein_id": "ENSP00000495528.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3641,
"cds_start": -4,
"cds_end": null,
"cds_length": 10926,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 11802,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 40,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "c.4396-25A>G",
"hgvs_p": null,
"transcript": "ENST00000645114.2",
"protein_id": "ENSP00000495884.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2726,
"cds_start": -4,
"cds_end": null,
"cds_length": 8181,
"cdna_start": null,
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"cdna_length": 8400,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "n.4515-25A>G",
"hgvs_p": null,
"transcript": "ENST00000643684.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"feature": null
},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "n.*400-25A>G",
"hgvs_p": null,
"transcript": "ENST00000643958.2",
"protein_id": "ENSP00000505734.1",
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"aa_start": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000645039.2",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 71,
"intron_rank": 20,
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"gene_symbol": "DYNC1H1",
"gene_hgnc_id": 2961,
"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000679486.1",
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},
{
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"strand": true,
"consequences": [
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],
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000679629.1",
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},
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],
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"intron_rank": 20,
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000679910.1",
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},
{
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"strand": true,
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],
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.*3905-25A>G",
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"transcript": "ENST00000680001.1",
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},
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],
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000680120.1",
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},
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],
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"intron_rank": 20,
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000680200.1",
"protein_id": "ENSP00000506166.1",
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},
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"strand": true,
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],
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},
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],
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"strand": true,
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],
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"intron_rank": 20,
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000680808.1",
"protein_id": "ENSP00000506446.1",
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"feature": null
},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 20,
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"gene_symbol": "DYNC1H1",
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"hgvs_c": "n.4396-25A>G",
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"transcript": "ENST00000680874.1",
"protein_id": "ENSP00000504911.1",
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}