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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 14-50980053-T-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=14&pos=50980053&ref=T&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "14",
"pos": 50980053,
"ref": "T",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000684578.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2163-504A>C",
"hgvs_p": null,
"transcript": "NM_001387360.1",
"protein_id": "NP_001374289.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 795,
"cds_start": -4,
"cds_end": null,
"cds_length": 2388,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4579,
"mane_select": "ENST00000684578.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2163-504A>C",
"hgvs_p": null,
"transcript": "ENST00000684578.1",
"protein_id": "ENSP00000507131.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 795,
"cds_start": -4,
"cds_end": null,
"cds_length": 2388,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4579,
"mane_select": "NM_001387360.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.1908-504A>C",
"hgvs_p": null,
"transcript": "ENST00000298355.7",
"protein_id": "ENSP00000298355.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 710,
"cds_start": -4,
"cds_end": null,
"cds_length": 2133,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5284,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2151-504A>C",
"hgvs_p": null,
"transcript": "ENST00000338969.9",
"protein_id": "ENSP00000342970.5",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 802,
"cds_start": -4,
"cds_end": null,
"cds_length": 2409,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3312,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2151-504A>C",
"hgvs_p": null,
"transcript": "NM_001387361.1",
"protein_id": "NP_001374290.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 791,
"cds_start": -4,
"cds_end": null,
"cds_length": 2376,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4567,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2139-504A>C",
"hgvs_p": null,
"transcript": "NM_001387362.1",
"protein_id": "NP_001374291.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 787,
"cds_start": -4,
"cds_end": null,
"cds_length": 2364,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4555,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2127-504A>C",
"hgvs_p": null,
"transcript": "NM_001387363.1",
"protein_id": "NP_001374292.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 783,
"cds_start": -4,
"cds_end": null,
"cds_length": 2352,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4543,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2121-504A>C",
"hgvs_p": null,
"transcript": "NM_001387364.1",
"protein_id": "NP_001374293.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 781,
"cds_start": -4,
"cds_end": null,
"cds_length": 2346,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4537,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2109-504A>C",
"hgvs_p": null,
"transcript": "NM_001387365.1",
"protein_id": "NP_001374294.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 777,
"cds_start": -4,
"cds_end": null,
"cds_length": 2334,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4525,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2097-504A>C",
"hgvs_p": null,
"transcript": "NM_001387366.1",
"protein_id": "NP_001374295.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 773,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.2085-504A>C",
"hgvs_p": null,
"transcript": "NM_001387367.1",
"protein_id": "NP_001374296.1",
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"aa_start": null,
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"cds_start": -4,
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},
{
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"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1974-504A>C",
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"transcript": "NM_001387368.1",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 9,
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1944-504A>C",
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"transcript": "NM_001387369.1",
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},
{
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],
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1932-504A>C",
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},
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],
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"gene_symbol": "TRIM9",
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"transcript": "NM_015163.6",
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},
{
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],
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"exon_count": 10,
"intron_rank": 8,
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1905-504A>C",
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},
{
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],
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1896-504A>C",
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"transcript": "NM_001387372.1",
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},
{
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 10,
"intron_rank": 8,
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1854-504A>C",
"hgvs_p": null,
"transcript": "NM_001387373.1",
"protein_id": "NP_001374302.1",
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},
{
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],
"exon_rank": null,
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"gene_symbol": "TRIM9",
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"hgvs_c": "c.1635-504A>C",
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"transcript": "NM_001387374.1",
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},
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],
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},
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],
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"gene_symbol": "TRIM9",
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},
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "c.1392-504A>C",
"hgvs_p": null,
"transcript": "NM_001387378.1",
"protein_id": "NP_001374307.1",
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"cds_start": -4,
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"mane_select": null,
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"feature": null
},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "TRIM9",
"gene_hgnc_id": 16288,
"hgvs_c": "n.513-504A>C",
"hgvs_p": null,
"transcript": "ENST00000555170.1",
"protein_id": null,
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