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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 16-57434496-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=16&pos=57434496&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "16",
"pos": 57434496,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_020313.4",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "NM_020313.4",
"protein_id": "NP_064709.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000394391.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_020313.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000394391.9",
"protein_id": "ENSP00000377914.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_020313.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000394391.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "ENST00000567518.5",
"protein_id": "ENSP00000456114.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 299,
"cds_start": null,
"cds_end": null,
"cds_length": 900,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000567518.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "ENST00000939128.1",
"protein_id": "ENSP00000609187.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 367,
"cds_start": null,
"cds_end": null,
"cds_length": 1104,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000939128.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000884888.1",
"protein_id": "ENSP00000554947.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 354,
"cds_start": null,
"cds_end": null,
"cds_length": 1065,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884888.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000884887.1",
"protein_id": "ENSP00000554946.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884887.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000884889.1",
"protein_id": "ENSP00000554948.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884889.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000884891.1",
"protein_id": "ENSP00000554950.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884891.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000939130.1",
"protein_id": "ENSP00000609189.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
"cds_end": null,
"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000939130.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000950775.1",
"protein_id": "ENSP00000620834.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 312,
"cds_start": null,
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"cds_length": 939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000950775.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000950773.1",
"protein_id": "ENSP00000620832.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 301,
"cds_start": null,
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"cds_length": 906,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000950773.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "NM_001308347.2",
"protein_id": "NP_001295276.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001308347.2"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "ENST00000939127.1",
"protein_id": "ENSP00000609186.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000939127.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 9,
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"gene_symbol": "CIAPIN1",
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"hgvs_c": "c.349-284A>G",
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"transcript": "ENST00000939129.1",
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},
{
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"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 10,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "ENST00000950774.1",
"protein_id": "ENSP00000620833.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000950774.1"
},
{
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"strand": false,
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],
"exon_rank": null,
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"intron_rank": 4,
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"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-371A>G",
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"transcript": "ENST00000884886.1",
"protein_id": "ENSP00000554945.1",
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"biotype": "protein_coding",
"feature": "ENST00000884886.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 8,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "NM_001308358.2",
"protein_id": "NP_001295287.1",
"transcript_support_level": null,
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"cds_start": null,
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"biotype": "protein_coding",
"feature": "NM_001308358.2"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 8,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000568940.5",
"protein_id": "ENSP00000454480.1",
"transcript_support_level": 3,
"aa_start": null,
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"cds_start": null,
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "CIAPIN1",
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"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000569370.5",
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},
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"consequences": [
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],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
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"hgvs_c": "c.388-284A>G",
"hgvs_p": null,
"transcript": "ENST00000569979.5",
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},
{
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"strand": false,
"consequences": [
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],
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"intron_rank": 3,
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"gene_symbol": "CIAPIN1",
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"hgvs_c": "c.307-284A>G",
"hgvs_p": null,
"transcript": "ENST00000565961.5",
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"transcript_support_level": 3,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000565961.5"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "CIAPIN1",
"gene_hgnc_id": 28050,
"hgvs_c": "c.349-284A>G",
"hgvs_p": null,
"transcript": "ENST00000884890.1",
"protein_id": "ENSP00000554949.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884890.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 2,
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}