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GeneBe API Showcase

This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.

API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.

Documentation & Advanced Usage

Complete API documentation:docs.genebe.net/docs/api/overview/

Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/

Python client for pandas:pypi.org/project/genebe/

Java CLI for VCF files:github.com/pstawinski/genebe-cli

All tools documented at:docs.genebe.net

API Request Examples for Variant: 17-47676459-G-A (hg38)

Bash / cURL Example

bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=47676459&ref=G&alt=A&genome=hg38&allGenes=true"

API Response

json
{
  "variants": [
    {
      "chr": "17",
      "pos": 47676459,
      "ref": "G",
      "alt": "A",
      "effect": "missense_variant",
      "transcript": "NM_002265.6",
      "consequences": [
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 16,
          "exon_rank_end": null,
          "exon_count": 22,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser",
          "transcript": "NM_002265.6",
          "protein_id": "NP_002256.2",
          "transcript_support_level": null,
          "aa_start": 655,
          "aa_end": null,
          "aa_length": 876,
          "cds_start": 1963,
          "cds_end": null,
          "cds_length": 2631,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": "ENST00000290158.9",
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_002265.6"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": true,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 16,
          "exon_rank_end": null,
          "exon_count": 22,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser",
          "transcript": "ENST00000290158.9",
          "protein_id": "ENSP00000290158.3",
          "transcript_support_level": 1,
          "aa_start": 655,
          "aa_end": null,
          "aa_length": 876,
          "cds_start": 1963,
          "cds_end": null,
          "cds_length": 2631,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": "NM_002265.6",
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000290158.9"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 17,
          "exon_rank_end": null,
          "exon_count": 23,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.2113G>A",
          "hgvs_p": "p.Gly705Ser",
          "transcript": "ENST00000931903.1",
          "protein_id": "ENSP00000601962.1",
          "transcript_support_level": null,
          "aa_start": 705,
          "aa_end": null,
          "aa_length": 926,
          "cds_start": 2113,
          "cds_end": null,
          "cds_length": 2781,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931903.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 17,
          "exon_rank_end": null,
          "exon_count": 23,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser",
          "transcript": "ENST00000583648.6",
          "protein_id": "ENSP00000464042.2",
          "transcript_support_level": 4,
          "aa_start": 655,
          "aa_end": null,
          "aa_length": 876,
          "cds_start": 1963,
          "cds_end": null,
          "cds_length": 2631,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000583648.6"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 17,
          "exon_rank_end": null,
          "exon_count": 23,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser",
          "transcript": "ENST00000931899.1",
          "protein_id": "ENSP00000601958.1",
          "transcript_support_level": null,
          "aa_start": 655,
          "aa_end": null,
          "aa_length": 876,
          "cds_start": 1963,
          "cds_end": null,
          "cds_length": 2631,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931899.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 17,
          "exon_rank_end": null,
          "exon_count": 23,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser",
          "transcript": "ENST00000931900.1",
          "protein_id": "ENSP00000601959.1",
          "transcript_support_level": null,
          "aa_start": 655,
          "aa_end": null,
          "aa_length": 876,
          "cds_start": 1963,
          "cds_end": null,
          "cds_length": 2631,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931900.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 16,
          "exon_rank_end": null,
          "exon_count": 22,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1942G>A",
          "hgvs_p": "p.Gly648Ser",
          "transcript": "ENST00000866807.1",
          "protein_id": "ENSP00000536866.1",
          "transcript_support_level": null,
          "aa_start": 648,
          "aa_end": null,
          "aa_length": 869,
          "cds_start": 1942,
          "cds_end": null,
          "cds_length": 2610,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000866807.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 16,
          "exon_rank_end": null,
          "exon_count": 22,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1939G>A",
          "hgvs_p": "p.Gly647Ser",
          "transcript": "ENST00000931905.1",
          "protein_id": "ENSP00000601964.1",
          "transcript_support_level": null,
          "aa_start": 647,
          "aa_end": null,
          "aa_length": 868,
          "cds_start": 1939,
          "cds_end": null,
          "cds_length": 2607,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931905.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1891G>A",
          "hgvs_p": "p.Gly631Ser",
          "transcript": "ENST00000866804.1",
          "protein_id": "ENSP00000536863.1",
          "transcript_support_level": null,
          "aa_start": 631,
          "aa_end": null,
          "aa_length": 852,
          "cds_start": 1891,
          "cds_end": null,
          "cds_length": 2559,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000866804.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1873G>A",
          "hgvs_p": "p.Gly625Ser",
          "transcript": "ENST00000931902.1",
          "protein_id": "ENSP00000601961.1",
          "transcript_support_level": null,
          "aa_start": 625,
          "aa_end": null,
          "aa_length": 846,
          "cds_start": 1873,
          "cds_end": null,
          "cds_length": 2541,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931902.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 16,
          "exon_rank_end": null,
          "exon_count": 22,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1825G>A",
          "hgvs_p": "p.Gly609Ser",
          "transcript": "ENST00000946082.1",
          "protein_id": "ENSP00000616141.1",
          "transcript_support_level": null,
          "aa_start": 609,
          "aa_end": null,
          "aa_length": 830,
          "cds_start": 1825,
          "cds_end": null,
          "cds_length": 2493,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000946082.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1771G>A",
          "hgvs_p": "p.Gly591Ser",
          "transcript": "ENST00000931901.1",
          "protein_id": "ENSP00000601960.1",
          "transcript_support_level": null,
          "aa_start": 591,
          "aa_end": null,
          "aa_length": 812,
          "cds_start": 1771,
          "cds_end": null,
          "cds_length": 2439,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931901.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1762G>A",
          "hgvs_p": "p.Gly588Ser",
          "transcript": "ENST00000866808.1",
          "protein_id": "ENSP00000536867.1",
          "transcript_support_level": null,
          "aa_start": 588,
          "aa_end": null,
          "aa_length": 809,
          "cds_start": 1762,
          "cds_end": null,
          "cds_length": 2430,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000866808.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 13,
          "exon_rank_end": null,
          "exon_count": 19,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1660G>A",
          "hgvs_p": "p.Gly554Ser",
          "transcript": "ENST00000866806.1",
          "protein_id": "ENSP00000536865.1",
          "transcript_support_level": null,
          "aa_start": 554,
          "aa_end": null,
          "aa_length": 775,
          "cds_start": 1660,
          "cds_end": null,
          "cds_length": 2328,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000866806.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 12,
          "exon_rank_end": null,
          "exon_count": 18,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1600G>A",
          "hgvs_p": "p.Gly534Ser",
          "transcript": "ENST00000931904.1",
          "protein_id": "ENSP00000601963.1",
          "transcript_support_level": null,
          "aa_start": 534,
          "aa_end": null,
          "aa_length": 755,
          "cds_start": 1600,
          "cds_end": null,
          "cds_length": 2268,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000931904.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1528G>A",
          "hgvs_p": "p.Gly510Ser",
          "transcript": "NM_001276453.2",
          "protein_id": "NP_001263382.1",
          "transcript_support_level": null,
          "aa_start": 510,
          "aa_end": null,
          "aa_length": 731,
          "cds_start": 1528,
          "cds_end": null,
          "cds_length": 2196,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001276453.2"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1528G>A",
          "hgvs_p": "p.Gly510Ser",
          "transcript": "ENST00000535458.6",
          "protein_id": "ENSP00000438253.2",
          "transcript_support_level": 2,
          "aa_start": 510,
          "aa_end": null,
          "aa_length": 731,
          "cds_start": 1528,
          "cds_end": null,
          "cds_length": 2196,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000535458.6"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 15,
          "exon_rank_end": null,
          "exon_count": 21,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1528G>A",
          "hgvs_p": "p.Gly510Ser",
          "transcript": "ENST00000540627.5",
          "protein_id": "ENSP00000438964.1",
          "transcript_support_level": 2,
          "aa_start": 510,
          "aa_end": null,
          "aa_length": 731,
          "cds_start": 1528,
          "cds_end": null,
          "cds_length": 2196,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000540627.5"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 12,
          "exon_rank_end": null,
          "exon_count": 18,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1435G>A",
          "hgvs_p": "p.Gly479Ser",
          "transcript": "ENST00000866805.1",
          "protein_id": "ENSP00000536864.1",
          "transcript_support_level": null,
          "aa_start": 479,
          "aa_end": null,
          "aa_length": 700,
          "cds_start": 1435,
          "cds_end": null,
          "cds_length": 2103,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000866805.1"
        },
        {
          "aa_ref": "G",
          "aa_alt": "S",
          "canonical": false,
          "protein_coding": true,
          "strand": true,
          "consequences": [
            "missense_variant"
          ],
          "exon_rank": 11,
          "exon_rank_end": null,
          "exon_count": 17,
          "intron_rank": null,
          "intron_rank_end": null,
          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "c.1402G>A",
          "hgvs_p": "p.Gly468Ser",
          "transcript": "ENST00000582097.5",
          "protein_id": "ENSP00000463066.1",
          "transcript_support_level": 2,
          "aa_start": 468,
          "aa_end": null,
          "aa_length": 689,
          "cds_start": 1402,
          "cds_end": null,
          "cds_length": 2070,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": null,
          "mane_select": null,
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        },
        {
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          "exon_count": 6,
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          "transcript": "ENST00000579901.5",
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          "aa_length": null,
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          "cds_length": null,
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          "cdna_length": null,
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          "biotype": "pseudogene",
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        {
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          "canonical": false,
          "protein_coding": false,
          "strand": true,
          "consequences": [
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          "exon_count": 6,
          "intron_rank": null,
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          "gene_symbol": "KPNB1",
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          "hgvs_c": "n.383G>A",
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          "transcript": "ENST00000580158.2",
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          "cds_length": null,
          "cdna_start": null,
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          "biotype": "retained_intron",
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        },
        {
          "aa_ref": null,
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          "canonical": false,
          "protein_coding": false,
          "strand": true,
          "consequences": [
            "non_coding_transcript_exon_variant"
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          "exon_count": 7,
          "intron_rank": null,
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          "gene_symbol": "KPNB1",
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          "hgvs_c": "n.746G>A",
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          "transcript": "ENST00000580573.2",
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          "transcript_support_level": 3,
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          "aa_length": null,
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          "biotype": "retained_intron",
          "feature": "ENST00000580573.2"
        },
        {
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          "canonical": false,
          "protein_coding": false,
          "strand": true,
          "consequences": [
            "non_coding_transcript_exon_variant"
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          "exon_count": 12,
          "intron_rank": null,
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          "gene_symbol": "KPNB1",
          "gene_hgnc_id": 6400,
          "hgvs_c": "n.844G>A",
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          "transcript": "ENST00000677341.1",
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          "cds_length": null,
          "cdna_start": null,
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          "cdna_length": null,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "retained_intron",
          "feature": "ENST00000677341.1"
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      ],
      "gene_symbol": "KPNB1",
      "gene_hgnc_id": 6400,
      "dbsnp": null,
      "frequency_reference_population": 0.0000013686724,
      "hom_count_reference_population": 0,
      "allele_count_reference_population": 2,
      "gnomad_exomes_af": 0.00000136867,
      "gnomad_genomes_af": null,
      "gnomad_exomes_ac": 2,
      "gnomad_genomes_ac": null,
      "gnomad_exomes_homalt": 0,
      "gnomad_genomes_homalt": null,
      "gnomad_mito_homoplasmic": null,
      "gnomad_mito_heteroplasmic": null,
      "computational_score_selected": 0.2278043031692505,
      "computational_prediction_selected": "Benign",
      "computational_source_selected": "MetaRNN",
      "splice_score_selected": 0.009999999776482582,
      "splice_prediction_selected": "Benign",
      "splice_source_selected": "max_spliceai",
      "revel_score": 0.096,
      "revel_prediction": "Benign",
      "alphamissense_score": 0.0763,
      "alphamissense_prediction": null,
      "bayesdelnoaf_score": -0.4,
      "bayesdelnoaf_prediction": "Benign",
      "phylop100way_score": 5.855,
      "phylop100way_prediction": "Uncertain_significance",
      "spliceai_max_score": 0.01,
      "spliceai_max_prediction": "Benign",
      "dbscsnv_ada_score": null,
      "dbscsnv_ada_prediction": null,
      "apogee2_score": null,
      "apogee2_prediction": null,
      "mitotip_score": null,
      "mitotip_prediction": null,
      "acmg_score": 0,
      "acmg_classification": "Uncertain_significance",
      "acmg_criteria": "PM2,BP4_Moderate",
      "acmg_by_gene": [
        {
          "score": 0,
          "benign_score": 2,
          "pathogenic_score": 2,
          "criteria": [
            "PM2",
            "BP4_Moderate"
          ],
          "verdict": "Uncertain_significance",
          "transcript": "NM_002265.6",
          "gene_symbol": "KPNB1",
          "hgnc_id": 6400,
          "effects": [
            "missense_variant"
          ],
          "inheritance_mode": "AD",
          "hgvs_c": "c.1963G>A",
          "hgvs_p": "p.Gly655Ser"
        }
      ],
      "clinvar_disease": "not specified",
      "clinvar_classification": "Uncertain significance",
      "clinvar_review_status": "criteria provided, single submitter",
      "clinvar_submissions_summary": "US:1",
      "phenotype_combined": "not specified",
      "pathogenicity_classification_combined": "Uncertain significance",
      "custom_annotations": null
    }
  ],
  "message": null
}
For research and educational, non-commercial use only. Not for clinical or diagnostic use. GeneBe does not provide medical advice. Data use for AI modeling is prohibited: if used, the cost is $0.001 per byte of downloaded uncompressed data.