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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-4897899-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=4897899&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 4897899,
"ref": "T",
"alt": "C",
"effect": "3_prime_UTR_variant",
"transcript": "NM_153827.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "n.*4280T>C",
"hgvs_p": null,
"transcript": "ENST00000574453.5",
"protein_id": "ENSP00000461500.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4941,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "NM_153827.5",
"protein_id": "NP_722549.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1332,
"cds_start": -4,
"cds_end": null,
"cds_length": 3999,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5017,
"mane_select": "ENST00000355280.11",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "ENST00000355280.11",
"protein_id": "ENSP00000347427.6",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1332,
"cds_start": -4,
"cds_end": null,
"cds_length": 3999,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5017,
"mane_select": "NM_153827.5",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CHRNE",
"gene_hgnc_id": 1966,
"hgvs_c": "c.*837A>G",
"hgvs_p": null,
"transcript": "NM_000080.4",
"protein_id": "NP_000071.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 493,
"cds_start": -4,
"cds_end": null,
"cds_length": 1482,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2482,
"mane_select": "ENST00000649488.2",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CHRNE",
"gene_hgnc_id": 1966,
"hgvs_c": "c.*837A>G",
"hgvs_p": null,
"transcript": "ENST00000649488.2",
"protein_id": "ENSP00000497829.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 493,
"cds_start": -4,
"cds_end": null,
"cds_length": 1482,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2482,
"mane_select": "NM_000080.4",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "ENST00000347992.11",
"protein_id": "ENSP00000269296.7",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1303,
"cds_start": -4,
"cds_end": null,
"cds_length": 3912,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4863,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "n.*4280T>C",
"hgvs_p": null,
"transcript": "ENST00000574453.5",
"protein_id": "ENSP00000461500.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4941,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 28,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "n.*3262T>C",
"hgvs_p": null,
"transcript": "ENST00000571207.5",
"protein_id": "ENSP00000459699.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4569,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "n.2989T>C",
"hgvs_p": null,
"transcript": "ENST00000574871.1",
"protein_id": null,
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3150,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CHRNE",
"gene_hgnc_id": 1966,
"hgvs_c": "n.2045A>G",
"hgvs_p": null,
"transcript": "ENST00000652550.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2173,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "NM_001024937.4",
"protein_id": "NP_001020108.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1312,
"cds_start": -4,
"cds_end": null,
"cds_length": 3939,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 4957,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "NM_170663.5",
"protein_id": "NP_733763.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1303,
"cds_start": -4,
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"cds_length": 3912,
"cdna_start": null,
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"cdna_length": 4930,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "NM_015716.5",
"protein_id": "NP_056531.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1295,
"cds_start": -4,
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"cds_length": 3888,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "NM_001321236.2",
"protein_id": "NP_001308165.1",
"transcript_support_level": null,
"aa_start": null,
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"feature": null
},
{
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"protein_coding": false,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 28,
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"exon_count": 28,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "n.*3262T>C",
"hgvs_p": null,
"transcript": "ENST00000571207.5",
"protein_id": "ENSP00000459699.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 4569,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 33,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
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"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "XM_006721531.2",
"protein_id": "XP_006721594.1",
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},
{
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"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 33,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
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"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "XM_006721532.2",
"protein_id": "XP_006721595.1",
"transcript_support_level": null,
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"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 33,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "XM_017024704.1",
"protein_id": "XP_016880193.1",
"transcript_support_level": null,
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"cds_start": -4,
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"cdna_start": null,
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},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 33,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
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"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
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"transcript": "XM_047436165.1",
"protein_id": "XP_047292121.1",
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},
{
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],
"exon_rank": 33,
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"intron_rank": null,
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"gene_symbol": "MINK1",
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},
{
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"protein_coding": true,
"strand": true,
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],
"exon_rank": 33,
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"exon_count": 33,
"intron_rank": null,
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"gene_symbol": "MINK1",
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"hgvs_c": "c.*612T>C",
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"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 33,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "XM_047436167.1",
"protein_id": "XP_047292123.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1337,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 5032,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 32,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MINK1",
"gene_hgnc_id": 17565,
"hgvs_c": "c.*612T>C",
"hgvs_p": null,
"transcript": "XM_047436168.1",
"protein_id": "XP_047292124.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": -4,
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"cdna_start": null,
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}