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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-73242948-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=73242948&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 73242948,
"ref": "G",
"alt": "C",
"effect": "synonymous_variant",
"transcript": "NM_017941.6",
"consequences": [
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "NM_001351264.2",
"protein_id": "NP_001338193.2",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000535032.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001351264.2"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000535032.7",
"protein_id": "ENSP00000440551.2",
"transcript_support_level": 1,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001351264.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000535032.7"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1566G>C",
"hgvs_p": "p.Thr522Thr",
"transcript": "ENST00000268942.12",
"protein_id": "ENSP00000268942.8",
"transcript_support_level": 1,
"aa_start": 522,
"aa_end": null,
"aa_length": 573,
"cds_start": 1566,
"cds_end": null,
"cds_length": 1722,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000268942.12"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "NM_017941.6",
"protein_id": "NP_060411.3",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_017941.6"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000359042.6",
"protein_id": "ENSP00000351937.2",
"transcript_support_level": 5,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000359042.6"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000893517.1",
"protein_id": "ENSP00000563576.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000893517.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000893518.1",
"protein_id": "ENSP00000563577.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000893518.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934364.1",
"protein_id": "ENSP00000604423.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934364.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934365.1",
"protein_id": "ENSP00000604424.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934365.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934366.1",
"protein_id": "ENSP00000604425.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934366.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934368.1",
"protein_id": "ENSP00000604427.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934368.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934369.1",
"protein_id": "ENSP00000604428.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934369.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000934371.1",
"protein_id": "ENSP00000604430.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000934371.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000953071.1",
"protein_id": "ENSP00000623130.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953071.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000953072.1",
"protein_id": "ENSP00000623131.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953072.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000953074.1",
"protein_id": "ENSP00000623133.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 609,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953074.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "NM_001100622.4",
"protein_id": "NP_001094092.2",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 583,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1752,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001100622.4"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "NM_001386978.1",
"protein_id": "NP_001373907.1",
"transcript_support_level": null,
"aa_start": 558,
"aa_end": null,
"aa_length": 583,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1752,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001386978.1"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1674G>C",
"hgvs_p": "p.Thr558Thr",
"transcript": "ENST00000426147.6",
"protein_id": "ENSP00000396970.2",
"transcript_support_level": 2,
"aa_start": 558,
"aa_end": null,
"aa_length": 583,
"cds_start": 1674,
"cds_end": null,
"cds_length": 1752,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000426147.6"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1566G>C",
"hgvs_p": "p.Thr522Thr",
"transcript": "NM_001100621.3",
"protein_id": "NP_001094091.2",
"transcript_support_level": null,
"aa_start": 522,
"aa_end": null,
"aa_length": 573,
"cds_start": 1566,
"cds_end": null,
"cds_length": 1722,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001100621.3"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1566G>C",
"hgvs_p": "p.Thr522Thr",
"transcript": "NM_001288770.3",
"protein_id": "NP_001275699.2",
"transcript_support_level": null,
"aa_start": 522,
"aa_end": null,
"aa_length": 573,
"cds_start": 1566,
"cds_end": null,
"cds_length": 1722,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001288770.3"
},
{
"aa_ref": "T",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTNAP1",
"gene_hgnc_id": 29601,
"hgvs_c": "c.1566G>C",
"hgvs_p": "p.Thr522Thr",
"transcript": "NM_001351265.2",
"protein_id": "NP_001338194.2",
"transcript_support_level": null,
"aa_start": 522,
"aa_end": null,
"aa_length": 573,
"cds_start": 1566,
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