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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-76685108-T-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=76685108&ref=T&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 76685108,
"ref": "T",
"alt": "A",
"effect": "missense_variant",
"transcript": "NM_001387276.1",
"consequences": [
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "NM_198530.4",
"protein_id": "NP_940932.2",
"transcript_support_level": null,
"aa_start": 155,
"aa_end": null,
"aa_length": 170,
"cds_start": 464,
"cds_end": null,
"cds_length": 513,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000449428.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_198530.4"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "ENST00000449428.7",
"protein_id": "ENSP00000391466.1",
"transcript_support_level": 1,
"aa_start": 155,
"aa_end": null,
"aa_length": 170,
"cds_start": 464,
"cds_end": null,
"cds_length": 513,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_198530.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000449428.7"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.593A>T",
"hgvs_p": "p.Lys198Met",
"transcript": "ENST00000592148.1",
"protein_id": "ENSP00000465103.1",
"transcript_support_level": 1,
"aa_start": 198,
"aa_end": null,
"aa_length": 213,
"cds_start": 593,
"cds_end": null,
"cds_length": 642,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000592148.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_premature_start_codon_gain_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000589082.1",
"protein_id": "ENSP00000467510.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 22,
"cds_start": null,
"cds_end": null,
"cds_length": 69,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000589082.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_premature_start_codon_gain_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000585519.5",
"protein_id": "ENSP00000466376.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 15,
"cds_start": null,
"cds_end": null,
"cds_length": 48,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000585519.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_premature_start_codon_gain_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000588114.5",
"protein_id": "ENSP00000468020.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 15,
"cds_start": null,
"cds_end": null,
"cds_length": 48,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000588114.5"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.593A>T",
"hgvs_p": "p.Lys198Met",
"transcript": "NM_001387276.1",
"protein_id": "NP_001374205.1",
"transcript_support_level": null,
"aa_start": 198,
"aa_end": null,
"aa_length": 247,
"cds_start": 593,
"cds_end": null,
"cds_length": 744,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001387276.1"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.593A>T",
"hgvs_p": "p.Lys198Met",
"transcript": "NM_001387277.1",
"protein_id": "NP_001374206.1",
"transcript_support_level": null,
"aa_start": 198,
"aa_end": null,
"aa_length": 220,
"cds_start": 593,
"cds_end": null,
"cds_length": 663,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001387277.1"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 2,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.593A>T",
"hgvs_p": "p.Lys198Met",
"transcript": "NM_001363769.2",
"protein_id": "NP_001350698.1",
"transcript_support_level": null,
"aa_start": 198,
"aa_end": null,
"aa_length": 213,
"cds_start": 593,
"cds_end": null,
"cds_length": 642,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363769.2"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "NM_001008528.3",
"protein_id": "NP_001008528.1",
"transcript_support_level": null,
"aa_start": 155,
"aa_end": null,
"aa_length": 204,
"cds_start": 464,
"cds_end": null,
"cds_length": 615,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001008528.3"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "ENST00000355797.7",
"protein_id": "ENSP00000348050.2",
"transcript_support_level": 2,
"aa_start": 155,
"aa_end": null,
"aa_length": 204,
"cds_start": 464,
"cds_end": null,
"cds_length": 615,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000355797.7"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "NM_001008529.3",
"protein_id": "NP_001008529.1",
"transcript_support_level": null,
"aa_start": 155,
"aa_end": null,
"aa_length": 177,
"cds_start": 464,
"cds_end": null,
"cds_length": 534,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001008529.3"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.464A>T",
"hgvs_p": "p.Lys155Met",
"transcript": "ENST00000375036.6",
"protein_id": "ENSP00000364176.1",
"transcript_support_level": 2,
"aa_start": 155,
"aa_end": null,
"aa_length": 177,
"cds_start": 464,
"cds_end": null,
"cds_length": 534,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000375036.6"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.371A>T",
"hgvs_p": "p.Lys124Met",
"transcript": "NM_001387278.1",
"protein_id": "NP_001374207.1",
"transcript_support_level": null,
"aa_start": 124,
"aa_end": null,
"aa_length": 173,
"cds_start": 371,
"cds_end": null,
"cds_length": 522,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001387278.1"
},
{
"aa_ref": "K",
"aa_alt": "M",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.371A>T",
"hgvs_p": "p.Lys124Met",
"transcript": "XM_047436104.1",
"protein_id": "XP_047292060.1",
"transcript_support_level": null,
"aa_start": 124,
"aa_end": null,
"aa_length": 139,
"cds_start": 371,
"cds_end": null,
"cds_length": 420,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047436104.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000589082.1",
"protein_id": "ENSP00000467510.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 22,
"cds_start": null,
"cds_end": null,
"cds_length": 69,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000589082.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000585519.5",
"protein_id": "ENSP00000466376.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 15,
"cds_start": null,
"cds_end": null,
"cds_length": 48,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000585519.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"5_prime_UTR_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "c.-2A>T",
"hgvs_p": null,
"transcript": "ENST00000588114.5",
"protein_id": "ENSP00000468020.1",
"transcript_support_level": 4,
"aa_start": null,
"aa_end": null,
"aa_length": 15,
"cds_start": null,
"cds_end": null,
"cds_length": 48,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000588114.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "n.183A>T",
"hgvs_p": null,
"transcript": "NR_130926.2",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "NR_130926.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "n.166A>T",
"hgvs_p": null,
"transcript": "NR_130927.2",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "NR_130927.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"hgvs_c": "n.166A>T",
"hgvs_p": null,
"transcript": "NR_130928.2",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "NR_130928.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "SNHG16",
"gene_hgnc_id": 44352,
"hgvs_c": "n.289-28738T>A",
"hgvs_p": null,
"transcript": "ENST00000738069.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000738069.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ENSG00000296346",
"gene_hgnc_id": null,
"hgvs_c": "n.133+13936T>A",
"hgvs_p": null,
"transcript": "ENST00000738461.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000738461.1"
}
],
"gene_symbol": "MXRA7",
"gene_hgnc_id": 7541,
"dbsnp": "rs144263669",
"frequency_reference_population": 0.00051551184,
"hom_count_reference_population": 1,
"allele_count_reference_population": 832,
"gnomad_exomes_af": 0.000545209,
"gnomad_genomes_af": 0.000230106,
"gnomad_exomes_ac": 797,
"gnomad_genomes_ac": 35,
"gnomad_exomes_homalt": 1,
"gnomad_genomes_homalt": 0,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": 0.10824465751647949,
"computational_prediction_selected": "Benign",
"computational_source_selected": "MetaRNN",
"splice_score_selected": 0,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": 0.132,
"revel_prediction": "Benign",
"alphamissense_score": 0.2698,
"alphamissense_prediction": null,
"bayesdelnoaf_score": -0.38,
"bayesdelnoaf_prediction": "Benign",
"phylop100way_score": 1.309,
"phylop100way_prediction": "Benign",
"spliceai_max_score": 0,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": -2,
"acmg_classification": "Likely_benign",
"acmg_criteria": "BP4_Moderate",
"acmg_by_gene": [
{
"score": -2,
"benign_score": 2,
"pathogenic_score": 0,
"criteria": [
"BP4_Moderate"
],
"verdict": "Likely_benign",
"transcript": "NM_001387276.1",
"gene_symbol": "MXRA7",
"hgnc_id": 7541,
"effects": [
"missense_variant"
],
"inheritance_mode": "AR",
"hgvs_c": "c.593A>T",
"hgvs_p": "p.Lys198Met"
},
{
"score": -2,
"benign_score": 2,
"pathogenic_score": 0,
"criteria": [
"BP4_Moderate"
],
"verdict": "Likely_benign",
"transcript": "ENST00000738069.1",
"gene_symbol": "SNHG16",
"hgnc_id": 44352,
"effects": [
"intron_variant"
],
"inheritance_mode": "",
"hgvs_c": "n.289-28738T>A",
"hgvs_p": null
},
{
"score": -2,
"benign_score": 2,
"pathogenic_score": 0,
"criteria": [
"BP4_Moderate"
],
"verdict": "Likely_benign",
"transcript": "ENST00000738461.1",
"gene_symbol": "ENSG00000296346",
"hgnc_id": null,
"effects": [
"intron_variant"
],
"inheritance_mode": "",
"hgvs_c": "n.133+13936T>A",
"hgvs_p": null
}
],
"clinvar_disease": "not specified",
"clinvar_classification": "Uncertain significance",
"clinvar_review_status": "criteria provided, single submitter",
"clinvar_submissions_summary": "US:1",
"phenotype_combined": "not specified",
"pathogenicity_classification_combined": "Uncertain significance",
"custom_annotations": null
}
],
"message": null
}