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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-7702407-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=7702407&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 7702407,
"ref": "A",
"alt": "G",
"effect": "missense_variant",
"transcript": "NM_018081.2",
"consequences": [
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "NM_001143992.2",
"protein_id": "NP_001137464.1",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000396463.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001143992.2"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000396463.7",
"protein_id": "ENSP00000379727.3",
"transcript_support_level": 1,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001143992.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000396463.7"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000316024.9",
"protein_id": "ENSP00000324203.5",
"transcript_support_level": 1,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000316024.9"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000431639.6",
"protein_id": "ENSP00000397219.2",
"transcript_support_level": 1,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000431639.6"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000457584.6",
"protein_id": "ENSP00000411061.2",
"transcript_support_level": 1,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000457584.6"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.920A>G",
"hgvs_p": "p.Tyr307Cys",
"transcript": "ENST00000534050.5",
"protein_id": "ENSP00000434999.1",
"transcript_support_level": 1,
"aa_start": 307,
"aa_end": null,
"aa_length": 515,
"cds_start": 920,
"cds_end": null,
"cds_length": 1548,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000534050.5"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1184A>G",
"hgvs_p": "p.Tyr395Cys",
"transcript": "ENST00000932535.1",
"protein_id": "ENSP00000602594.1",
"transcript_support_level": null,
"aa_start": 395,
"aa_end": null,
"aa_length": 603,
"cds_start": 1184,
"cds_end": null,
"cds_length": 1812,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000932535.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1037A>G",
"hgvs_p": "p.Tyr346Cys",
"transcript": "ENST00000868854.1",
"protein_id": "ENSP00000538913.1",
"transcript_support_level": null,
"aa_start": 346,
"aa_end": null,
"aa_length": 554,
"cds_start": 1037,
"cds_end": null,
"cds_length": 1665,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868854.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1037A>G",
"hgvs_p": "p.Tyr346Cys",
"transcript": "ENST00000932533.1",
"protein_id": "ENSP00000602592.1",
"transcript_support_level": null,
"aa_start": 346,
"aa_end": null,
"aa_length": 554,
"cds_start": 1037,
"cds_end": null,
"cds_length": 1665,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000932533.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "NM_001143990.2",
"protein_id": "NP_001137462.1",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001143990.2"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "NM_001143991.2",
"protein_id": "NP_001137463.1",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001143991.2"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "NM_018081.2",
"protein_id": "NP_060551.2",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 548,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_018081.2"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.968A>G",
"hgvs_p": "p.Tyr323Cys",
"transcript": "ENST00000932534.1",
"protein_id": "ENSP00000602593.1",
"transcript_support_level": null,
"aa_start": 323,
"aa_end": null,
"aa_length": 531,
"cds_start": 968,
"cds_end": null,
"cds_length": 1596,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000932534.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.962A>G",
"hgvs_p": "p.Tyr321Cys",
"transcript": "ENST00000868853.1",
"protein_id": "ENSP00000538912.1",
"transcript_support_level": null,
"aa_start": 321,
"aa_end": null,
"aa_length": 529,
"cds_start": 962,
"cds_end": null,
"cds_length": 1590,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000868853.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.920A>G",
"hgvs_p": "p.Tyr307Cys",
"transcript": "ENST00000964568.1",
"protein_id": "ENSP00000634627.1",
"transcript_support_level": null,
"aa_start": 307,
"aa_end": null,
"aa_length": 515,
"cds_start": 920,
"cds_end": null,
"cds_length": 1548,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000964568.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000698746.1",
"protein_id": "ENSP00000513908.1",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 503,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1512,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000698746.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys",
"transcript": "ENST00000698742.1",
"protein_id": "ENSP00000513904.1",
"transcript_support_level": null,
"aa_start": 340,
"aa_end": null,
"aa_length": 469,
"cds_start": 1019,
"cds_end": null,
"cds_length": 1410,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000698742.1"
},
{
"aa_ref": "Y",
"aa_alt": "C",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "c.611A>G",
"hgvs_p": "p.Tyr204Cys",
"transcript": "ENST00000698747.1",
"protein_id": "ENSP00000513909.1",
"transcript_support_level": null,
"aa_start": 204,
"aa_end": null,
"aa_length": 412,
"cds_start": 611,
"cds_end": null,
"cds_length": 1239,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000698747.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "n.1691A>G",
"hgvs_p": null,
"transcript": "ENST00000467699.5",
"protein_id": null,
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "retained_intron",
"feature": "ENST00000467699.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "n.290A>G",
"hgvs_p": null,
"transcript": "ENST00000471973.6",
"protein_id": null,
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "retained_intron",
"feature": "ENST00000471973.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "n.*187A>G",
"hgvs_p": null,
"transcript": "ENST00000498311.5",
"protein_id": "ENSP00000432991.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000498311.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"hgvs_c": "n.*752A>G",
"hgvs_p": null,
"transcript": "ENST00000698743.1",
"protein_id": "ENSP00000513905.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
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{
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"canonical": false,
"protein_coding": false,
"strand": true,
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],
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},
{
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"protein_coding": false,
"strand": true,
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},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
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],
"exon_rank": 8,
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"gene_symbol": "WRAP53",
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"hgvs_c": "n.*187A>G",
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"transcript": "ENST00000498311.5",
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},
{
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"protein_coding": false,
"strand": true,
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],
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},
{
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"protein_coding": false,
"strand": true,
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],
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"gene_symbol": "WRAP53",
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{
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"protein_coding": false,
"strand": true,
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"3_prime_UTR_variant"
],
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"gene_symbol": "WRAP53",
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"biotype": "nonsense_mediated_decay",
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},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
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"exon_count": 4,
"intron_rank": 1,
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"gene_symbol": "WRAP53",
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"hgvs_c": "n.134-336A>G",
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"transcript": "ENST00000463804.6",
"protein_id": "ENSP00000465025.1",
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"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
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"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000463804.6"
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],
"gene_symbol": "WRAP53",
"gene_hgnc_id": 25522,
"dbsnp": "rs1555530889",
"frequency_reference_population": null,
"hom_count_reference_population": 0,
"allele_count_reference_population": 0,
"gnomad_exomes_af": null,
"gnomad_genomes_af": null,
"gnomad_exomes_ac": null,
"gnomad_genomes_ac": null,
"gnomad_exomes_homalt": null,
"gnomad_genomes_homalt": null,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": 0.8329943418502808,
"computational_prediction_selected": "Pathogenic",
"computational_source_selected": "MetaRNN",
"splice_score_selected": 0.009999999776482582,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": 0.544,
"revel_prediction": "Uncertain_significance",
"alphamissense_score": 0.5837,
"alphamissense_prediction": null,
"bayesdelnoaf_score": 0.15,
"bayesdelnoaf_prediction": "Pathogenic",
"phylop100way_score": 4.783,
"phylop100way_prediction": "Uncertain_significance",
"spliceai_max_score": 0.01,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": 3,
"acmg_classification": "Uncertain_significance",
"acmg_criteria": "PM2,PP3",
"acmg_by_gene": [
{
"score": 3,
"benign_score": 0,
"pathogenic_score": 3,
"criteria": [
"PM2",
"PP3"
],
"verdict": "Uncertain_significance",
"transcript": "NM_018081.2",
"gene_symbol": "WRAP53",
"hgnc_id": 25522,
"effects": [
"missense_variant"
],
"inheritance_mode": "AR,AD",
"hgvs_c": "c.1019A>G",
"hgvs_p": "p.Tyr340Cys"
}
],
"clinvar_disease": "not specified",
"clinvar_classification": "Uncertain significance",
"clinvar_review_status": "criteria provided, single submitter",
"clinvar_submissions_summary": "US:1",
"phenotype_combined": "not specified",
"pathogenicity_classification_combined": "Uncertain significance",
"custom_annotations": null
}
],
"message": null
}