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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 17-79115648-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=17&pos=79115648&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "17",
"pos": 79115648,
"ref": "G",
"alt": "A",
"effect": "missense_variant",
"transcript": "ENST00000693108.1",
"consequences": [
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001350451.2",
"protein_id": "NP_001337380.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 613,
"cdna_end": null,
"cdna_length": 3163,
"mane_select": "ENST00000693108.1",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "ENST00000693108.1",
"protein_id": "ENSP00000510395.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 613,
"cdna_end": null,
"cdna_length": 3163,
"mane_select": "NM_001350451.2",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385804.1",
"protein_id": "NP_001372733.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 373,
"cds_start": 68,
"cds_end": null,
"cds_length": 1122,
"cdna_start": 613,
"cdna_end": null,
"cdna_length": 2317,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385805.1",
"protein_id": "NP_001372734.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 373,
"cds_start": 68,
"cds_end": null,
"cds_length": 1122,
"cdna_start": 633,
"cdna_end": null,
"cdna_length": 2337,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385806.1",
"protein_id": "NP_001372735.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 372,
"cds_start": 68,
"cds_end": null,
"cds_length": 1119,
"cdna_start": 613,
"cdna_end": null,
"cdna_length": 2314,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385807.1",
"protein_id": "NP_001372736.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 858,
"cdna_end": null,
"cdna_length": 3408,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385808.1",
"protein_id": "NP_001372737.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 782,
"cdna_end": null,
"cdna_length": 3332,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385809.1",
"protein_id": "NP_001372738.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 682,
"cdna_end": null,
"cdna_length": 3232,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385810.1",
"protein_id": "NP_001372739.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 440,
"cdna_end": null,
"cdna_length": 2990,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385811.1",
"protein_id": "NP_001372740.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 1284,
"cdna_end": null,
"cdna_length": 3834,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385812.1",
"protein_id": "NP_001372741.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 1244,
"cdna_end": null,
"cdna_length": 3794,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385813.1",
"protein_id": "NP_001372742.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 802,
"cdna_end": null,
"cdna_length": 3352,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385814.1",
"protein_id": "NP_001372743.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 573,
"cdna_end": null,
"cdna_length": 3123,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385815.1",
"protein_id": "NP_001372744.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
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"cdna_start": 745,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385816.1",
"protein_id": "NP_001372745.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 882,
"cdna_end": null,
"cdna_length": 3432,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385817.1",
"protein_id": "NP_001372746.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
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"cdna_start": 610,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": "A",
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385818.1",
"protein_id": "NP_001372747.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
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"cdna_start": 684,
"cdna_end": null,
"cdna_length": 3234,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385819.1",
"protein_id": "NP_001372748.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 686,
"cdna_end": null,
"cdna_length": 3236,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385820.1",
"protein_id": "NP_001372749.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
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"cdna_start": 748,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385821.1",
"protein_id": "NP_001372750.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 359,
"cds_start": 68,
"cds_end": null,
"cds_length": 1080,
"cdna_start": 849,
"cdna_end": null,
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"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385822.1",
"protein_id": "NP_001372751.1",
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"aa_start": 23,
"aa_end": null,
"aa_length": 358,
"cds_start": 68,
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"cdna_start": 613,
"cdna_end": null,
"cdna_length": 3160,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "NM_001385823.1",
"protein_id": "NP_001372752.1",
"transcript_support_level": null,
"aa_start": 23,
"aa_end": null,
"aa_length": 358,
"cds_start": 68,
"cds_end": null,
"cds_length": 1077,
"cdna_start": 686,
"cdna_end": null,
"cdna_length": 3233,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "A",
"aa_alt": "V",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "RBFOX3",
"gene_hgnc_id": 27097,
"hgvs_c": "c.68C>T",
"hgvs_p": "p.Ala23Val",
"transcript": "ENST00000583458.5",
"protein_id": "ENSP00000464186.1",
"transcript_support_level": 5,
"aa_start": 23,
"aa_end": null,
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