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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 18-9149439-A-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=18&pos=9149439&ref=A&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "18",
"pos": 9149439,
"ref": "A",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_015208.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "NM_015208.5",
"protein_id": "NP_056023.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2062,
"cds_start": null,
"cds_end": null,
"cds_length": 6189,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000262126.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_015208.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000262126.9",
"protein_id": "ENSP00000262126.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 2062,
"cds_start": null,
"cds_end": null,
"cds_length": 6189,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_015208.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000262126.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "ENST00000400020.7",
"protein_id": "ENSP00000382897.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 2039,
"cds_start": null,
"cds_end": null,
"cds_length": 6120,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000400020.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "n.161+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000540578.6",
"protein_id": null,
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000540578.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12464A>C",
"hgvs_p": null,
"transcript": "ENST00000917028.1",
"protein_id": "ENSP00000587087.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2062,
"cds_start": null,
"cds_end": null,
"cds_length": 6189,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000917028.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000962123.1",
"protein_id": "ENSP00000632182.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2060,
"cds_start": null,
"cds_end": null,
"cds_length": 6183,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000962123.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "NM_001083625.3",
"protein_id": "NP_001077094.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2039,
"cds_start": null,
"cds_end": null,
"cds_length": 6120,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001083625.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "NM_001204056.1",
"protein_id": "NP_001190985.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2039,
"cds_start": null,
"cds_end": null,
"cds_length": 6120,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001204056.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000917029.1",
"protein_id": "ENSP00000587088.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2039,
"cds_start": null,
"cds_end": null,
"cds_length": 6120,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000917029.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000917031.1",
"protein_id": "ENSP00000587090.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1991,
"cds_start": null,
"cds_end": null,
"cds_length": 5976,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000917031.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "ENST00000917030.1",
"protein_id": "ENSP00000587089.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1948,
"cds_start": null,
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"cds_length": 5847,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000917030.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+13084A>C",
"hgvs_p": null,
"transcript": "ENST00000585234.5",
"protein_id": "ENSP00000464422.1",
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": 43,
"cds_start": null,
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"cds_length": 134,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000585234.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 2,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12343A>C",
"hgvs_p": null,
"transcript": "ENST00000577992.1",
"protein_id": "ENSP00000462312.1",
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": 11,
"cds_start": null,
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"cds_length": 38,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000577992.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12343A>C",
"hgvs_p": null,
"transcript": "XM_005258093.5",
"protein_id": "XP_005258150.1",
"transcript_support_level": null,
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"cdna_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_005258093.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11850A>C",
"hgvs_p": null,
"transcript": "XM_024451107.2",
"protein_id": "XP_024306875.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2062,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_024451107.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "XM_047437386.1",
"protein_id": "XP_047293342.1",
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047437386.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12474A>C",
"hgvs_p": null,
"transcript": "XM_005258095.4",
"protein_id": "XP_005258152.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 2060,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_005258095.4"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12343A>C",
"hgvs_p": null,
"transcript": "XM_017025661.3",
"protein_id": "XP_016881150.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2060,
"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "XM_017025661.3"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "XM_017025662.3",
"protein_id": "XP_016881151.1",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "XM_047437387.1",
"protein_id": "XP_047293343.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
"feature": "XM_047437387.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+12343A>C",
"hgvs_p": null,
"transcript": "XM_017025663.3",
"protein_id": "XP_016881152.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017025663.3"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ANKRD12",
"gene_hgnc_id": 29135,
"hgvs_c": "c.-52+11566A>C",
"hgvs_p": null,
"transcript": "XM_047437388.1",
"protein_id": "XP_047293344.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2039,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047437388.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
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}
],
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}