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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 2-115444847-A-G (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=115444847&ref=A&alt=G&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "2",
"pos": 115444847,
"ref": "A",
"alt": "G",
"effect": "intron_variant",
"transcript": "ENST00000410059.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.272-54663A>G",
"hgvs_p": null,
"transcript": "NM_020868.6",
"protein_id": "NP_065919.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 796,
"cds_start": -4,
"cds_end": null,
"cds_length": 2391,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5964,
"mane_select": "ENST00000410059.6",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.272-54663A>G",
"hgvs_p": null,
"transcript": "ENST00000410059.6",
"protein_id": "ENSP00000386565.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 796,
"cds_start": -4,
"cds_end": null,
"cds_length": 2391,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5964,
"mane_select": "NM_020868.6",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.284-54663A>G",
"hgvs_p": null,
"transcript": "ENST00000393147.6",
"protein_id": "ENSP00000376855.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 800,
"cds_start": -4,
"cds_end": null,
"cds_length": 2403,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2758,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.251-54663A>G",
"hgvs_p": null,
"transcript": "ENST00000310323.12",
"protein_id": "ENSP00000309066.8",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 789,
"cds_start": -4,
"cds_end": null,
"cds_length": 2370,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3052,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.323-54663A>G",
"hgvs_p": null,
"transcript": "NM_001321905.3",
"protein_id": "NP_001308834.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 813,
"cds_start": -4,
"cds_end": null,
"cds_length": 2442,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 6388,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.284-54663A>G",
"hgvs_p": null,
"transcript": "NM_001178034.1",
"protein_id": "NP_001171505.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 800,
"cds_start": -4,
"cds_end": null,
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"cdna_start": null,
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"cdna_length": 4829,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.260-54663A>G",
"hgvs_p": null,
"transcript": "NM_001178037.3",
"protein_id": "NP_001171508.2",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 792,
"cds_start": -4,
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"cdna_start": null,
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"cdna_length": 5999,
"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.251-54663A>G",
"hgvs_p": null,
"transcript": "NM_001004360.5",
"protein_id": "NP_001004360.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 789,
"cds_start": -4,
"cds_end": null,
"cds_length": 2370,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 5884,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "DPP10",
"gene_hgnc_id": 20823,
"hgvs_c": "c.251-54663A>G",
"hgvs_p": null,
"transcript": "NM_001321906.2",
"protein_id": "NP_001308835.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": -4,
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"mane_select": null,
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},
{
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],
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"gene_symbol": "DPP10",
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"hgvs_c": "c.272-54663A>G",
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"transcript": "NM_001321907.3",
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},
{
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],
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"gene_symbol": "DPP10",
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"hgvs_c": "c.182-54663A>G",
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},
{
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],
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],
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],
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"gene_symbol": "DPP10",
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],
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},
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],
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"gene_symbol": "DPP10",
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"hgvs_c": "c.260-54663A>G",
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